loading...| Preferred Name |
prion disease |
| Synonyms |
spongiform encephalopathy prion induced disorder prion protein disease prion disease pathway |
| Definitions |
A transmissible disease that is caused by a protein that is able to induce abnormal folding of normal cellular proteins, leading to characteristic spongiform brain changes, which are associated with neuronal loss without an inflammatory response. Such disorders have typically long incubation periods, but are then generally rapidly progressive and are uniformly fatal. Editor note: check relationship to spongiform encephalopathy NCIT:C27585 |
| ID |
http://purl.obolibrary.org/obo/MONDO_0005429 |
| comment |
Editor note: check relationship to spongiform encephalopathy NCIT:C27585 |
| database_cross_reference |
MESH:D017096 NCIT:C128346 ICD9:046.19 EFO:0004720 DOID:649 SCTID:230284004 |
| definition |
A transmissible disease that is caused by a protein that is able to induce abnormal folding of normal cellular proteins, leading to characteristic spongiform brain changes, which are associated with neuronal loss without an inflammatory response. Such disorders have typically long incubation periods, but are then generally rapidly progressive and are uniformly fatal. |
| exactMatch |
http://purl.obolibrary.org/obo/DOID_649 http://purl.obolibrary.org/obo/NCIT_C128346 |
| has_exact_synonym |
spongiform encephalopathy prion induced disorder prion protein disease prion disease pathway |
| id |
MONDO:0005429 |
| label |
prion disease |
| notation |
MONDO:0005429 |
| prefLabel |
prion disease |
| treeView | |
| subClassOf |