loading...| Preferred Name |
Cefonicid Sodium |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C65300 |
| CAS_Registry |
61270-78-8 |
| CHEBI_ID |
CHEBI:3492 |
| Chemical_Formula |
C18H16N6O8S3.2Na |
| code |
C65300 |
| Concept_In_Subset | |
| Contributing_Source |
FDA |
| DEFINITION |
The sodium salt form of cefonicid, a semisynthetic second-generation cephalosporin with antibacterial activity. Cefonicid binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis. |
| FDA_UNII_Code |
F74MFL78A1 |
| FULL_SYN |
Cefonicid Sodium CEFONICID SODIUM |
| Has_Free_Acid_Or_Base_Form | |
| label |
Cefonicid Sodium |
| Legacy Concept Name |
Cefonicid_Sodium |
| Preferred_Name |
Cefonicid Sodium |
| prefixIRI |
Thesaurus:C65300 |
| prefLabel |
Cefonicid Sodium |
| Semantic_Type |
Pharmacologic Substance |
| UMLS_CUI |
C0886812 |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.obolibrary.org/obo/CHEBI_3492 | Chemical Entities of Biological Interest Ontology / 生物相关的化学实体本体 | LOOM |