Preferred Name

esophagus

Definitions

将咽部连接到胃部的管道。在哺乳动物中,食管连接颊腔和胃。衬在颊腔内的复层鳞状非角化上皮继续通过咽下行进入食管。食管的最底下部分(约2厘米)内衬胃粘膜并覆盖腹膜。食道主体内衬小而简单的粘液腺。每个腺体通过一条穿透粘膜肌层的长导管向腔内开放(Wilson和Washington,1989)。括约肌位于食管进入胃部的位置,以防止胃食管反流,即防止酸性胃内容物到达食管的复层上皮细胞,并在那里引起炎症和刺激(Wilson and Washington,1989; Brown et al。 1993)。 Tube that connects the pharynx to the stomach. In mammals, the oesophagus connects the buccal cavity with the stomach. The stratified squamous non-keratinised epithelium lining the buccal cavity is continued through the pharynx down into the oesophagus. The lowest part of the oesophagus (ca. 2 cm) is lined with gastric mucosa and covered by peritoneum. The main body of the oesophagus is lined with small, simple mucous glands. Each gland opens into the lumen by a long duct which pierces the muscularis mucosae (Wilson and Washington, 1989). A sphincter is situated at the point where the oesophagus enters the stomach to prevent gastro-oesophageal reflux, i.e. to prevent acidic gastric contents from reaching stratified epithelia of the oesophagus, where they can cause inflammation and irritation (Wilson and Washington, 1989; Brown et al., 1993).

ID

http://purl.obolibrary.org/obo/UBERON_0001043

depicted_by

http://upload.wikimedia.org/wikipedia/commons/d/d4/Illu01_head_neck.jpg

hasDbXref

ANISEED:1235301

CALOHA:TS-0700

OpenCyc:Mx4rvVj9Q5wpEbGdrcN5Y29ycA

EV:0100069

XAO:0000127

GAID:291

BTO:0000959

EMAPA:16833

UMLS:C0014876

AAO:0000145

FMA:7131

MESH:A03.365

VHOG:0000450

MA:0000352

galen:Esophagus

MAT:0000048

TAO:0000204

MIAA:0000048

EFO:0000835

ZFA:0000204

EHDAA2:0001285

EHDAA:2937

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C12389

http://linkedlifedata.com/resource/umls/id/C0014876

http://en.wikipedia.org/wiki/Esophagus

http://www.snomedbrowser.com/Codes/Details/181245004

hasExactSynonym

gullet

食道

食管

oesophagus

hasOBONamespace

uberon

id

UBERON:0001043

inSubset

http://purl.obolibrary.org/obo/uberon/core#major_organ

http://purl.obolibrary.org/obo/uberon/core#uberon_slim

http://purl.obolibrary.org/obo/uberon/core#organ_slim

http://purl.obolibrary.org/obo/uberon/core#pheno_slim

http://purl.obolibrary.org/obo/uberon/core#efo_slim

http://purl.obolibrary.org/obo/uberon/core#vertebrate_core

label

esophagus

食管

prefixIRI

UBERON:0001043

prefLabel

esophagus

textual definition

将咽部连接到胃部的管道。在哺乳动物中,食管连接颊腔和胃。衬在颊腔内的复层鳞状非角化上皮继续通过咽下行进入食管。食管的最底下部分(约2厘米)内衬胃粘膜并覆盖腹膜。食道主体内衬小而简单的粘液腺。每个腺体通过一条穿透粘膜肌层的长导管向腔内开放(Wilson和Washington,1989)。括约肌位于食管进入胃部的位置,以防止胃食管反流,即防止酸性胃内容物到达食管的复层上皮细胞,并在那里引起炎症和刺激(Wilson and Washington,1989; Brown et al。 1993)。

Tube that connects the pharynx to the stomach. In mammals, the oesophagus connects the buccal cavity with the stomach. The stratified squamous non-keratinised epithelium lining the buccal cavity is continued through the pharynx down into the oesophagus. The lowest part of the oesophagus (ca. 2 cm) is lined with gastric mucosa and covered by peritoneum. The main body of the oesophagus is lined with small, simple mucous glands. Each gland opens into the lumen by a long duct which pierces the muscularis mucosae (Wilson and Washington, 1989). A sphincter is situated at the point where the oesophagus enters the stomach to prevent gastro-oesophageal reflux, i.e. to prevent acidic gastric contents from reaching stratified epithelia of the oesophagus, where they can cause inflammation and irritation (Wilson and Washington, 1989; Brown et al., 1993).

同源_注释

在(成年七鳃鳗)咽部的少数结构特化包括在外部鳃开口上的复杂瓣膜,其引导潮汐流,以及将祖先咽部分成食管和呼吸咽部。[建立得很好][VHOG]

The few structural specializations in (adult lampreys) pharynx include complex valves on the external gill openings that direct the tidal flow, and the division of the ancestral pharynx into an oesophagus and a respiratory pharynx.[well established][VHOG]

外部_定义

消化道的前端衬有平滑肌。由咽部的收缩向前界定。由与胃相关的圆形和/或纵向平滑肌向后界定和增加。[AAO]

Anterior end of the alimentary canal lined with smooth muscle. Bounded anteriorly by a constriction in the pharynx. Bounded posteriorly by and increase in circular and/or longitudinal smooth muscle associated with the stomach.[AAO]

外部_本体_注释

食管不是MA中的肠的一部分。ZFA中的肠的一部分。FMA中的肠的一部分(通过UGIT)。考虑分裂。种间:人类食管长25厘米,直径约2厘米。在大鼠、兔和猪的食道中仅发现很少的信息。大鼠(75 × 2mm)和兔的食管没有粘液腺,胃的贲门有发育良好的括约肌,防止它们呕吐(Hebel and Stromberg, 1988; Manning et al., 1994).在形态学上,人和猪的食道是相似的;两者都是杂食的,并具有非角化上皮、粘膜下层腺体和相似的膜酶。像人类一样,猪也会患反流性食管炎和食道应激性溃疡。因此猪食管与人食管相比可能是用于研究的良好模型(Christie et al., 1995)

esophagus NOT part of gut in MA. part of gut in ZFA. part_of gut (via UGIT) in FMA. Consider splitting. Interspecies: The human oesophagus is 25 cm long and has a diameter of ca. 2 cm. Only little information was found on the oesophagus in rat, rabbit and pig. The oesophagus of rat (75 x 2 mm) and rabbit has no mucous glands and the cardia of the stomach has a well-developed sphincter, which prevents them from vomiting (Hebel and Stromberg, 1988; Manning et al., 1994). Morphologically the oesophagus is similar in man and pig; both are omnivores and have a non-keratinised epithelium, submucous glands and similar membrane enzymes. Like in humans, pigs can suffer from reflux oesophagitis and stress ulceration of the oesophagus. The pig oesophagus may therefore be a good model for investigation compared to the human oesophagus (Christie et al., 1995)

引自

http://purl.obolibrary.org/obo/uberon.owl

http://purl.obolibrary.org/obo/clo.owl

有_关系_形容词

esophageal

食管

subClassOf

http://purl.obolibrary.org/obo/UBERON_0005181

http://purl.obolibrary.org/obo/UBERON_0004921

http://purl.obolibrary.org/obo/UBERON_0000062

http://purl.obolibrary.org/obo/UBERON_0013765

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http://purl.bioontology.org/ontology/LNC/MTHU011962 Logical Observation Identifier Names and Codes LOOM
http://purl.obolibrary.org/obo/BTO_0000959 BRENDA Tissue and Enzyme Source Ontology LOOM
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http://purl.org/sig/ont/fma/fma7131 Foundational Model of Anatomy LOOM
http://purl.bioontology.org/ontology/LNC/LA4018-3 Logical Observation Identifier Names and Codes LOOM