GenEpiO

Last uploaded: February 25, 2019
Preferred Name

esophagus

Definitions

Tube that connects the pharynx to the stomach. In mammals, the oesophagus connects the buccal cavity with the stomach. The stratified squamous non-keratinised epithelium lining the buccal cavity is continued through the pharynx down into the oesophagus. The lowest part of the oesophagus (ca. 2 cm) is lined with gastric mucosa and covered by peritoneum. The main body of the oesophagus is lined with small, simple mucous glands. Each gland opens into the lumen by a long duct which pierces the muscularis mucosae (Wilson and Washington, 1989). A sphincter is situated at the point where the oesophagus enters the stomach to prevent gastro-oesophageal reflux, i.e. to prevent acidic gastric contents from reaching stratified epithelia of the oesophagus, where they can cause inflammation and irritation (Wilson and Washington, 1989; Brown et al., 1993).

ID

http://purl.obolibrary.org/obo/UBERON_0001043

imported from

http://purl.obolibrary.org/obo/uberon.owl

label

esophagus

prefixIRI

UBERON:0001043

prefLabel

esophagus

textual definition

Tube that connects the pharynx to the stomach. In mammals, the oesophagus connects the buccal cavity with the stomach. The stratified squamous non-keratinised epithelium lining the buccal cavity is continued through the pharynx down into the oesophagus. The lowest part of the oesophagus (ca. 2 cm) is lined with gastric mucosa and covered by peritoneum. The main body of the oesophagus is lined with small, simple mucous glands. Each gland opens into the lumen by a long duct which pierces the muscularis mucosae (Wilson and Washington, 1989). A sphincter is situated at the point where the oesophagus enters the stomach to prevent gastro-oesophageal reflux, i.e. to prevent acidic gastric contents from reaching stratified epithelia of the oesophagus, where they can cause inflammation and irritation (Wilson and Washington, 1989; Brown et al., 1993).

subClassOf

http://purl.obolibrary.org/obo/UBERON_0004921

http://purl.obolibrary.org/obo/UBERON_0005178

http://purl.obolibrary.org/obo/UBERON_0013765

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http://purl.bioontology.org/ontology/LNC/MTHU011962 Logical Observation Identifier Names and Codes LOOM
http://purl.obolibrary.org/obo/BTO_0000959 BRENDA Tissue and Enzyme Source Ontology LOOM
http://purl.obolibrary.org/obo/UBERON_0001043 Human Phenotype Ontology China LOOM
http://purl.obolibrary.org/obo/UBERON_0001043 Human Phenotype Ontology China SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001043 Cell Ontology LOOM
http://purl.obolibrary.org/obo/UBERON_0001043 Cell Ontology SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001043 Cell Line Ontology Subset for Chinese National Infrastructure of Cell Line Resource (NICR) LOOM
http://purl.obolibrary.org/obo/UBERON_0001043 Cell Line Ontology Subset for Chinese National Infrastructure of Cell Line Resource (NICR) SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001043 International Classification of Diseases Ontology LOOM
http://purl.obolibrary.org/obo/UBERON_0001043 International Classification of Diseases Ontology SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001043 Uber Anatomy Ontology LOOM
http://purl.obolibrary.org/obo/UBERON_0001043 Uber Anatomy Ontology SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001043 Cell Line Ontology (Chinese Translation) SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001043 Human Disease Ontology LOOM
http://purl.obolibrary.org/obo/UBERON_0001043 Human Disease Ontology SAME_URI
http://purl.bioontology.org/ontology/MESH/D004947 Medical Subject Headings LOOM
http://purl.bioontology.org/ontology/LNC/LP199925-1 Logical Observation Identifier Names and Codes LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C12389 National Cancer Institute Thesaurus LOOM
http://purl.bioontology.org/ontology/LNC/LP29941-9 Logical Observation Identifier Names and Codes LOOM
http://purl.org/sig/ont/fma/fma7131 Foundational Model of Anatomy LOOM
http://purl.bioontology.org/ontology/LNC/LA4018-3 Logical Observation Identifier Names and Codes LOOM