loading...| Preferred Name |
Complement C4-B |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128866 |
| code |
C128866 |
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 |
| Contributing_Source |
CTRP |
| DEFINITION |
Complement C4-B (1744 aa, ~193 kDa) is encoded by the human C4B and C4B_2 genes. This protein is involved in the propagation of the classical complement pathway. |
| DesignNote |
Complement C4-B is cleaved into the following 6 chains: complement C4 beta chain, complement C4-B alpha chain, C4a anaphylatoxin, C4b-B, C4d-B, and complement C4 gamma chain. (UniProt) Complement C4-A and Complement C4-B differ by 4 amino acids at positions 1101-1106; C4A has the sequence PCPVLD, while C4B has the sequence LSPVIH. (OMIM) |
| Display_Name |
Complement C4-B |
| FULL_SYN |
C4B C3 and PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 2 Basic C4 Complement Component 4B Basic Complement C4 Complement C4-B Complement Component 4F Chido Form of C4 |
| label |
Complement C4-B |
| OMIM_Number |
120820 |
| Preferred_Name |
Complement C4-B |
| prefixIRI |
Thesaurus:C128866 |
| prefLabel |
Complement C4-B |
| Semantic_Type |
Amino Acid, Peptide, or Protein |
| Swiss_Prot |
P0C0L5 |
| UMLS_CUI |
C0009518 |
| subClassOf |