Preferred Name

Toxic Shock Syndrome

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C35498

ALT_DEFINITION

A rare acute life-threatening systemic bacterial noncontagious illness caused by staphylococcal exotoxins.

Profoundly reduced blood flow that results in impaired tissue perfusion and possible end organ damage resulting from an exotoxin released from certain bacteria, most often Staphylococcus aureus, or Streptococcus pyogenes.

code

C35498

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C189762

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118464

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62596

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128453

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C54450

Contributing_Source

MedDRA

NICHD

FDA

DEFINITION

A rare acute life-threatening systemic bacterial noncontagious illness caused by any of several related staphylococcal exotoxins. It is characterized by high fever, hypotension, rash, multi-organ dysfunction, and cutaneous desquamation during the early convalescent period. The toxins affect the host immune system, causing an exuberant and pathological host inflammatory response. Laboratory findings include leukocytosis, elevated prothrombin time, hypoalbuminemia, hypocalcemia, and pyuria.

FDA_Table

Patient Code (Appendix B)

FULL_SYN

Toxic Shock Syndrome

TSS

label

Toxic Shock Syndrome

Legacy Concept Name

Toxic_Shock_Syndrome

Maps_To

Toxic shock syndrome

Preferred_Name

Toxic Shock Syndrome

prefixIRI

Thesaurus:C35498

prefLabel

Toxic Shock Syndrome

Semantic_Type

Disease or Syndrome

UMLS_CUI

C0600327

xRef

IMDRF:E1414

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28193

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