Preferred Name

cerebrospinal fluid

Synonyms

spinal fluid

cerebral spinal fluid

CSF

liquor cerebrospinalis

Definitions

A clear, colorless, bodily fluid, that occupies the subarachnoid space and the ventricular system around and inside the brain and spinal cord.

ID

http://purl.obolibrary.org/obo/UBERON_0001359

contains

http://purl.obolibrary.org/obo/UBERON_0014930

http://purl.obolibrary.org/obo/UBERON_0000315

database_cross_reference

BIRNLEX:1798

BTO:0000237

CALOHA:TS-0130

GAID:1181

ENVO:02000029

MAT:0000499

FMA:20935

ZFA:0001626

TAO:0002184

Wikipedia:Cerebrospinal_fluid

EHDAA2:0004441

EFO:0000329

MA:0002503

EV:0100311

NCIT:C12692

UMLS:C0007806

VHOG:0001278

MESH:D002555

definition

A clear, colorless, bodily fluid, that occupies the subarachnoid space and the ventricular system around and inside the brain and spinal cord.

develops_from

http://purl.obolibrary.org/obo/UBERON_0002307

editor note

many sources state the CP as sole producer of CSF, but this is disputed [DOI:10.1007/s11064-015-1581-6]

external_definition

Portion of organism substance that is a clear fluid that occupies the subarachnoid space and the ventricular system around and inside the brain.[TAO]

external_ontology_notes

the FMA def states that this is subarachnoid spaces only. ZFA def states subarachnoid spaces and brain ventricles, but not SC (and has part_of to brain). Circulation: It circulates from the lateral ventricles to the foramen of Monro (Interventricular foramen), third ventricle, aqueduct of Sylvius (Cerebral aqueduct), fourth ventricle, foramen of Magendie (Median aperture) and foramina of Luschka (Lateral apertures), subarachnoid space over brain and spinal cord. It should be noted that the CSF moves in a pulsatile manner throughout the CSF system with nearly zero net flow. CSF is reabsorbed into venous sinus blood via arachnoid granulations.

EHDAA2 models this as developing from CP, which is wrong

filtered through

http://purl.obolibrary.org/obo/UBERON_0001886

has exact synonym

cerebral spinal fluid

CSF

has related synonym

spinal fluid

liquor cerebrospinalis

has_obo_namespace

uberon

homology_notes

In vertebrates, at early stages of Central Nervous System (CNS) development, the architecture of the brain primordium reveals the presence of the cavity of brain vesicles, which is filled by Embryonic Cerebro-Spinal Fluid (E-CSF). (...) Rat and chick E-CSF proteomes are similar, although rat is more complex in certain groups of proteins, e.g., apolipoproteins, which may be involved in the control of neural diversity, and has soluble enzymes present, just like adult human CSF, but unlike chick E-CSF, revealing phylogenetic brain differences between these groups of vertebrates.[uncertain][VHOG]

id

UBERON:0001359

in_subset

http://purl.obolibrary.org/obo/uberon/core#uberon_slim

http://purl.obolibrary.org/obo/uberon/core#pheno_slim

http://purl.obolibrary.org/obo/uberon/core#efo_slim

http://purl.obolibrary.org/obo/uberon/core#vertebrate_core

label

cerebrospinal fluid

located in

http://purl.obolibrary.org/obo/UBERON_0005281

notation

UBERON:0001359

prefLabel

cerebrospinal fluid

treeView

http://purl.obolibrary.org/obo/UBERON_0002307

http://purl.obolibrary.org/obo/UBERON_0014930

http://purl.obolibrary.org/obo/UBERON_0000315

subClassOf

http://purl.obolibrary.org/obo/UBERON_0007779

Delete Subject Author Type Created
No notes to display
Create New Mapping

Delete Mapping To Ontology Source
http://purl.bmicc.cn/ontology/ICD11CN/XA1N55 《国际疾病分类》第11版中文版 / International Classification of Diseases, 11th Edition, China LOOM
http://purl.obolibrary.org/obo/BTO_0000237 BRENDA Tissue and Enzyme Source Ontology / 布兰达组织和酶源本体 LOOM
http://purl.bioontology.org/ontology/MESH/Q000134 Medical Subject Headings / 医学主题词表 LOOM
http://purl.obolibrary.org/obo/UBERON_0001359 Ontology of Adverse Events / 不良事件本体 LOOM
http://purl.obolibrary.org/obo/UBERON_0001359 Ontology of Adverse Events / 不良事件本体 SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001359 中国人类表型本体 / Human Phenotype Ontology China LOOM
http://purl.obolibrary.org/obo/UBERON_0001359 中国人类表型本体 / Human Phenotype Ontology China SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001359 Ontology for Biomedical Investigations / 生物医学研究本体 LOOM
http://purl.obolibrary.org/obo/UBERON_0001359 Ontology for Biomedical Investigations / 生物医学研究本体 SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001359 Coronavirus Infectious Disease Ontology / 冠状病毒感染性疾病本体 LOOM
http://purl.obolibrary.org/obo/UBERON_0001359 Coronavirus Infectious Disease Ontology / 冠状病毒感染性疾病本体 SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001359 Ontology for Biobanking / 生物样本库本体 LOOM
http://purl.obolibrary.org/obo/UBERON_0001359 Ontology for Biobanking / 生物样本库本体 SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001359 Experimental Factor Ontology / 实验性因素本体 LOOM
http://purl.obolibrary.org/obo/UBERON_0001359 Experimental Factor Ontology / 实验性因素本体 SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001359 Informed Consent Ontology / 知情同意本体 LOOM
http://purl.obolibrary.org/obo/UBERON_0001359 Informed Consent Ontology / 知情同意本体 SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001359 Environment Ontology / 环境本体 LOOM
http://purl.obolibrary.org/obo/UBERON_0001359 Environment Ontology / 环境本体 SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001359 GenEpiO / 基因组流行病学本体 LOOM
http://purl.obolibrary.org/obo/UBERON_0001359 GenEpiO / 基因组流行病学本体 SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001359 Cell Ontology / 细胞本体 LOOM
http://purl.obolibrary.org/obo/UBERON_0001359 Cell Ontology / 细胞本体 SAME_URI
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C12692 National Cancer Institute Thesaurus / 美国国家癌症研究所词典 LOOM
http://purl.bioontology.org/ontology/MESH/D002555 Medical Subject Headings / 医学主题词表 LOOM