loading...| Preferred Name |
cefalotin |
| Synonyms |
Cefalotin cefalotinum 7-(2-Thienylacetamido)cephalosporanic acid Cephalotin Cephalothin (6R,7R)-3-(acetoxymethyl)-8-oxo-7-(thiophen-2-ylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid cefalotina 7beta-(thiophen-2-ylacetamido)-3-acetoxymethyl-3,4-didehydrocepham-4-carboxylic acid Cefalothin 7-(2'-thienylacetamido)cephalosporanic acid cefalotin CEPHALOTHIN 7-(Thiophene-2-acetamido)cephalosporin cefalotine 3-Acetoxymethyl-7-(2-thienylacetamido)-3-cephem-4-carboxylic acid CET |
| Definitions |
A semisynthetic, first-generation cephalosporin antibiotic with acetoxymethyl and (2-thienylacetyl)nitrilo moieties at positions 3 and 7, respectively, of the core structure. Administered parenterally during surgery and to treat a wide spectrum of blood infections. |
| ID |
http://purl.obolibrary.org/obo/CHEBI_124991 |
| charge |
0 |
| database_cross_reference |
Reaxys:945586 PMID:23680238 PMID:23472927 Drug_Central:574 PMID:12833570 PMID:6176550 DrugBank:DB00456 PMID:10930630 PMID:29017833 Wikipedia:Cephalothin PMID:12569987 Patent:US3218318 LINCS:LSM-15184 KEGG:C07761 Beilstein:945586 PDBeChem:CLS PMID:13963283 KEGG:D07635 CAS:153-61-7 HMDB:HMDB0014599 PMID:2083978 PMID:1701026 PMID:1384868 Patent:FR1384197 |
| definition |
A semisynthetic, first-generation cephalosporin antibiotic with acetoxymethyl and (2-thienylacetyl)nitrilo moieties at positions 3 and 7, respectively, of the core structure. Administered parenterally during surgery and to treat a wide spectrum of blood infections. |
| formula |
C16H16N2O6S2 |
| has role | |
| has_alternative_id |
CHEBI:50895 CHEBI:41547 |
| has_exact_synonym |
Cefalotin (6R,7R)-3-(acetoxymethyl)-8-oxo-7-(thiophen-2-ylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 7beta-(thiophen-2-ylacetamido)-3-acetoxymethyl-3,4-didehydrocepham-4-carboxylic acid |
| has_obo_namespace |
chebi_ontology |
| has_related_synonym |
cefalotinum 7-(2-Thienylacetamido)cephalosporanic acid Cephalotin Cephalothin cefalotina Cefalothin 7-(2'-thienylacetamido)cephalosporanic acid cefalotin CEPHALOTHIN 7-(Thiophene-2-acetamido)cephalosporin cefalotine 3-Acetoxymethyl-7-(2-thienylacetamido)-3-cephem-4-carboxylic acid CET |
| id |
CHEBI:124991 |
| in_subset | |
| inchi |
InChI=1S/C16H16N2O6S2/c1-8(19)24-6-9-7-26-15-12(14(21)18(15)13(9)16(22)23)17-11(20)5-10-3-2-4-25-10/h2-4,12,15H,5-7H2,1H3,(H,17,20)(H,22,23)/t12-,15-/m1/s1 |
| inchikey |
XIURVHNZVLADCM-IUODEOHRSA-N |
| is conjugate acid of | |
| label |
cefalotin |
| mass |
396.43800 |
| monoisotopicmass |
396.04498 |
| notation |
CHEBI:124991 |
| prefLabel |
cefalotin |
| smiles |
[H][C@@]1(NC(=O)Cc2cccs2)C(=O)N2C(C(O)=O)=C(COC(C)=O)CS[C@]12[H] |
| treeView |
http://purl.obolibrary.org/obo/CHEBI_88225 http://purl.obolibrary.org/obo/CHEBI_33575 http://purl.obolibrary.org/obo/CHEBI_50896 http://purl.obolibrary.org/obo/CHEBI_23066 |
| subClassOf |
http://purl.obolibrary.org/obo/CHEBI_88225 http://purl.obolibrary.org/obo/CHEBI_33575 http://purl.obolibrary.org/obo/CHEBI_50896 http://purl.obolibrary.org/obo/CHEBI_23066 |