Preferred Name

viral dsRNA:TLR3 complex

Synonyms

(vir)dsRNA:TLR3

Definitions

A macromolecular complex that is composed of viral double stranded RNA (dsRNA) and a homodimer of TLR3. Viral dsRNA triggers an antiviral pathway mediated by Toll-like receptor 3. TLR3 dimerization occurs upon ligand binding to positively charged residues on the ectodomain termini of TLR3 wich are responsible for the interaction with sugar-phosphate groups of dsRNA. Category=complex. Requested by=TLR.

ID

http://purl.obolibrary.org/obo/PR_000037302

comment

Category=complex. Requested by=TLR.

definition

A macromolecular complex that is composed of viral double stranded RNA (dsRNA) and a homodimer of TLR3. Viral dsRNA triggers an antiviral pathway mediated by Toll-like receptor 3. TLR3 dimerization occurs upon ligand binding to positively charged residues on the ectodomain termini of TLR3 wich are responsible for the interaction with sugar-phosphate groups of dsRNA.

has_exact_synonym

(vir)dsRNA:TLR3

has_obo_namespace

protein

id

PR:000037302

label

viral dsRNA:TLR3 complex

notation

PR:000037302

prefLabel

viral dsRNA:TLR3 complex

treeView

http://purl.obolibrary.org/obo/GO_0032991

subClassOf

http://purl.obolibrary.org/obo/GO_0032991

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