Protein Ontology / 蛋白质本体

Last uploaded: March 7, 2023
Preferred Name

IRF3/IRF7:p-tbk1/p-IKKE:ticam1:ticam2:activated TLR4 complex

Synonyms

activated TLR4:TRAM:TRIF:p-TBK1/p-IKKE:IRF3/IRF7

Definitions

A protein-containing complex that is composed of activated Toll-like receptor 4 (TLR4), Ticam2, Ticam1, a phosphorylated kinase tbk1 or IKK epsilon and the non-phosphorylated form of IRF3 or IRF7. IRF3 and IRF7 are recruited via phosphorylated tbk1 and IKK epsilon. Category=complex. Requested by=TLR.

ID

http://purl.obolibrary.org/obo/PR_000028699

comment

Category=complex. Requested by=TLR.

definition

A protein-containing complex that is composed of activated Toll-like receptor 4 (TLR4), Ticam2, Ticam1, a phosphorylated kinase tbk1 or IKK epsilon and the non-phosphorylated form of IRF3 or IRF7. IRF3 and IRF7 are recruited via phosphorylated tbk1 and IKK epsilon.

has_obo_namespace

protein

has_related_synonym

activated TLR4:TRAM:TRIF:p-TBK1/p-IKKE:IRF3/IRF7

id

PR:000028699

label

IRF3/IRF7:p-tbk1/p-IKKE:ticam1:ticam2:activated TLR4 complex

notation

PR:000028699

prefLabel

IRF3/IRF7:p-tbk1/p-IKKE:ticam1:ticam2:activated TLR4 complex

treeView

http://purl.obolibrary.org/obo/GO_0032991

subClassOf

http://purl.obolibrary.org/obo/GO_0032991

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