loading...| Preferred Name |
Hepatolenticular Degeneration |
| Synonyms |
Hepatolenticular degeneration |
| Definitions |
<p>Wilson disease is a rare inherited disorder that prevents your body from getting rid of extra copper. You need a small amount of copper from food to stay healthy. Too much copper is poisonous.</p> <p>Normally, your liver releases extra copper into bile, a digestive fluid. With Wilson disease, the copper builds up in your liver, and it releases the copper directly into your bloodstream. This can cause damage to your brain, kidneys, and eyes.</p> <p>Wilson disease is present at birth, but symptoms usually start between ages 5 and 35. It first attacks the liver, the central nervous system or both. The most characteristic sign is a rusty brown ring around the cornea of the eye. A physical exam and laboratory tests can diagnose it.</p> <p>Treatment is with drugs to remove the extra copper from your body. You need to take medicine and follow a low-copper diet for the rest of your life. Don't eat shellfish or liver, as these foods may contain high levels of copper. At the beginning of treatment, you'll also need to avoid chocolate, mushrooms, and nuts. Have your drinking water checked for copper content and don't take multivitamins that contain copper.</p> <p>With early detection and proper treatment, you can enjoy good health.</p> <p class="">NIH: National Institute of Diabetes and Digestive and Kidney Diseases</p> |
| ID |
http://purl.bioontology.org/ontology/MEDLINEPLUS/C0019202 |
| altLabel |
Hepatolenticular degeneration Copper storage disease Copper Storage Disease Wilson Disease |
| cui |
C0019202 |
| Date created |
06/20/2002 |
| definition |
Wilson disease is a rare inherited disorder that prevents your body from getting rid of extra copper. You need a small amount of copper from food to stay healthy. Too much copper is poisonous. Normally, your liver releases extra copper into bile, a digestive fluid. With Wilson disease, the copper builds up in your liver, and it releases the copper directly into your bloodstream. This can cause damage to your brain, kidneys, and eyes. Wilson disease is present at birth, but symptoms usually start between ages 5 and 35. It first attacks the liver, the central nervous system or both. The most characteristic sign is a rusty brown ring around the cornea of the eye. A physical exam and laboratory tests can diagnose it. Treatment is with drugs to remove the extra copper from your body. You need to take medicine and follow a low-copper diet for the rest of your life. Don't eat shellfish or liver, as these foods may contain high levels of copper. At the beginning of treatment, you'll also need to avoid chocolate, mushrooms, and nuts. Have your drinking water checked for copper content and don't take multivitamins that contain copper. With early detection and proper treatment, you can enjoy good health. NIH: National Institute of Diabetes and Digestive and Kidney Diseases |
| Inverse of RQ | |
| Inverse of SY | |
| Mapped from | |
| Mapped to | |
| MP OTHER LANGUAGE URL | |
| MP PRIMARY INSTITUTE URL |
National Institute of Diabetes and Digestive and Kidney Diseases https://www.niddk.nih.gov |
| notation |
C0019202 |
| prefLabel |
Hepatolenticular Degeneration |
| Related to |
http://purl.bioontology.org/ontology/MEDLINEPLUS/C1456542 |
| Scope Statement |
Wilson disease is a disorder that prevents your body from getting rid of extra copper. Too much copper can affect the liver and nervous system.https://medlineplus.gov/wilsondisease.html |
| tui |
T047 |
| subClassOf |
http://purl.bioontology.org/ontology/MEDLINEPLUS/C1456603 http://purl.bioontology.org/ontology/MEDLINEPLUS/C2362500 |