Preferred Name

Liver Cirrhosis

Synonyms

Cirrhosis

Definitions

<p>Cirrhosis is scarring of the liver. Scar tissue forms because of injury or long-term disease. Scar tissue cannot do what healthy liver tissue does - make protein, help fight infections, clean the blood, help digest food and store energy. Cirrhosis can lead to :</p><ul> <li>Easy bruising or bleeding, or nosebleeds</li> <li>Swelling of the abdomen or legs </li> <li>Extra sensitivity to medicines</li> <li>High blood pressure in the vein entering the liver</li> <li>Enlarged veins called varices in the esophagus and stomach. Varices can bleed suddenly.</li> <li> Kidney failure</li> <li>Jaundice</li> <li>Severe itching</li> <li>Gallstones</li> </ul> <p>A small number of people with cirrhosis get <a href="https://medlineplus.gov/livercancer.html">liver cancer</a>.</p> <p>Your doctor will diagnose cirrhosis with blood tests, imaging tests, or a biopsy.</p> <p>Cirrhosis has many causes. In the United States, the most common causes are chronic <a href="https://medlineplus.gov/alcoholusedisorderaud.html">alcoholism</a> and <a href="https://medlineplus.gov/hepatitis.html">hepatitis</a>. Nothing will make the scar tissue disappear, but treating the cause can keep it from getting worse. If too much scar tissue forms, you may need to consider a <a href="https://medlineplus.gov/livertransplantation.html">liver transplant</a>. </p> <p class="">NIH: National Institute of Diabetes and Digestive and Kidney Diseases</p>

ID

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0023890

altLabel

Cirrhosis

cui

C0023890

Date created

07/08/1999

definition

Cirrhosis is scarring of the liver. Scar tissue forms because of injury or long-term disease. Scar tissue cannot do what healthy liver tissue does - make protein, help fight infections, clean the blood, help digest food and store energy. Cirrhosis can lead to :

  • Easy bruising or bleeding, or nosebleeds
  • Swelling of the abdomen or legs
  • Extra sensitivity to medicines
  • High blood pressure in the vein entering the liver
  • Enlarged veins called varices in the esophagus and stomach. Varices can bleed suddenly.
  • Kidney failure
  • Jaundice
  • Severe itching
  • Gallstones

A small number of people with cirrhosis get liver cancer.

Your doctor will diagnose cirrhosis with blood tests, imaging tests, or a biopsy.

Cirrhosis has many causes. In the United States, the most common causes are chronic alcoholism and hepatitis. Nothing will make the scar tissue disappear, but treating the cause can keep it from getting worse. If too much scar tissue forms, you may need to consider a liver transplant.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases

Inverse of RQ

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0023890

Inverse of SY

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0239946

Mapped from

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0023890

Mapped to

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0023890

MP OTHER LANGUAGE URL

Spanish https://medlineplus.gov/spanish/cirrhosis.html

MP PRIMARY INSTITUTE URL

National Institute of Diabetes and Digestive and Kidney Diseases https://www.niddk.nih.gov

notation

C0023890

prefLabel

Liver Cirrhosis

Related to

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0016977

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0001956

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0023895

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0023911

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0345904

Scope Statement

Cirrhosis is caused when scar tissue replaces healthy tissue in the liver because of chronic injury. Learn how cirrhosis is diagnosed and treated.https://medlineplus.gov/cirrhosis.html

tui

T047

subClassOf

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0012240

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Delete Mapping To Ontology Source
http://purl.bioontology.org/ontology/OMIM/MTHU008711 Online Mendelian Inheritance in Man / 在线人类孟德尔遗传数据库 CUI
http://purl.bioontology.org/ontology/OMIM/MTHU002081 Online Mendelian Inheritance in Man / 在线人类孟德尔遗传数据库 CUI
http://purl.obolibrary.org/obo/DOID_5082 BioAssay Ontology / 生物活性分析本体 LOOM
http://purl.obolibrary.org/obo/DOID_5082 Human Disease Ontology / 人类疾病本体 LOOM
http://purl.bioontology.org/ontology/MESH/D008103 Medical Subject Headings / 医学主题词表 CUI
http://purl.bioontology.org/ontology/MESH/D008103 Medical Subject Headings / 医学主题词表 LOOM
http://purl.bioontology.org/ontology/OMIM/MTHU018550 Online Mendelian Inheritance in Man / 在线人类孟德尔遗传数据库 CUI
http://purl.bioontology.org/ontology/OMIM/MTHU018550 Online Mendelian Inheritance in Man / 在线人类孟德尔遗传数据库 LOOM
http://purl.bioontology.org/ontology/ICD10CM/K74.60 International Classification of Diseases, Version 10 - Clinical Modification / 国际疾病分类,第10版-临床修改 CUI