loading...| Preferred Name |
von Willebrand Factor |
| Synonyms |
Factor VIIIR-RCo |
| Definitions |
A high-molecular-weight plasma protein, produced by endothelial cells and megakaryocytes, that is part of the factor VIII/von Willebrand factor complex. The von Willebrand factor has receptors for collagen, platelets, and ristocetin activity as well as the immunologically distinct antigenic determinants. It functions in adhesion of platelets to collagen and hemostatic plug formation. The prolonged bleeding time in VON WILLEBRAND DISEASES is due to the deficiency of this factor. |
| ID |
http://purl.bioontology.org/ontology/MESH/D014841 |
| altLabel |
Factor VIIIR-RCo Factor VIII-Related Antigen Factor VIIIR Ag Ristocetin Cofactor Plasma Factor VIII Complex Factor VIIIR-Ag Factor VIII Related Antigen Ristocetin Willebrand Factor Ristocetin-Willebrand Factor von Willebrand Protein Factor VIIIR RCo |
| AN |
/ defic = VON WILLEBRAND DISEASE or specific type of Von Willebrand Disease |
| AQL |
AA AD AE AG AI AN BI CF CH CL CS DE EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR |
| cui |
C0042971 C0032114 |
| DC |
1 |
| definition |
A high-molecular-weight plasma protein, produced by endothelial cells and megakaryocytes, that is part of the factor VIII/von Willebrand factor complex. The von Willebrand factor has receptors for collagen, platelets, and ristocetin activity as well as the immunologically distinct antigenic determinants. It functions in adhesion of platelets to collagen and hemostatic plug formation. The prolonged bleeding time in VON WILLEBRAND DISEASES is due to the deficiency of this factor. |
| DX |
19860101 |
| FX |
D056728 D020302 D056725 D056729 D014842 D003029 |
| HN |
86(76); was see under BLOOD COAGULATION FACTORS 1976-85; FACTOR VIII RELATED ANTIGEN, previously in the Supplementary Chemical File, was mapped to both FACTOR VIII & ANTIGENS 1977-89 |
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000528 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000600 |
| Inverse of RB |
0 |
| Inverse of RO |
http://purl.bioontology.org/ontology/MESH/D056729 http://purl.bioontology.org/ontology/MESH/D003029 http://purl.bioontology.org/ontology/MESH/D014842 http://purl.bioontology.org/ontology/MESH/D020302 |
| Machine permutation |
86; was see under BLOOD COAGULATION FACTORS 1976-85 |
| Mapped from |
http://purl.bioontology.org/ontology/MESH/C473097 http://purl.bioontology.org/ontology/MESH/C081839 http://purl.bioontology.org/ontology/MESH/C044131 http://purl.bioontology.org/ontology/MESH/C568131 http://purl.bioontology.org/ontology/MESH/C509423 http://purl.bioontology.org/ontology/MESH/C050818 http://purl.bioontology.org/ontology/MESH/C069815 http://purl.bioontology.org/ontology/MESH/C090953 http://purl.bioontology.org/ontology/MESH/C067003 http://purl.bioontology.org/ontology/MESH/C029417 |
| MDA |
19750725 |
| MMR |
20090706 |
| MN |
D12.776.124.125.920 D23.119.985 |
| notation |
D014841 |
| OL |
use FACTOR VIII & ANTIGENS to search FACTOR VIII RELATED ANTIGEN 1977-89 |
| prefLabel |
von Willebrand Factor |
| TERMUI |
T043381 T043379 T043378 T043377 T043376 T043380 T043382 T043384 |
| TH |
UNK (19XX) NLM (1990) NLM (1976) |
| tui |
T116 T121 T123 |
| subClassOf |