loading...| Preferred Name |
Imipenem |
| Synonyms |
Anhydrous, Imipenem |
| Definitions |
Semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. It is stable to beta-lactamases. Clinical studies have demonstrated high efficacy in the treatment of infections of various body systems. Its effectiveness is enhanced when it is administered in combination with CILASTATIN, a renal dipeptidase inhibitor. |
| ID |
http://purl.bioontology.org/ontology/MESH/D015378 |
| altLabel |
Anhydrous, Imipenem MK 0787 Anhydrous Imipenem MK0787 Imipenem, Anhydrous 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-3-((2-((iminomethyl)amino)ethyl)thio)-7-oxo-, (5R-(5alpha,6alpha(R*)))- N Formimidoylthienamycin Imipemide N-Formimidoylthienamycin Imipenem Anhydrous MK-0787 |
| AQL |
AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR |
| cui |
C0020933 C0886855 C0729073 |
| DC |
1 |
| definition |
Semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. It is stable to beta-lactamases. Clinical studies have demonstrated high efficacy in the treatment of infections of various body systems. Its effectiveness is enhanced when it is administered in combination with CILASTATIN, a renal dipeptidase inhibitor. |
| DX |
19890101 |
| HN |
89 |
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000528 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000378 |
| Inverse of RB |
71OTZ9ZE0A 0 Q20IM7HE75 |
| isa | |
| Machine permutation |
89 |
| Mapped from |
http://purl.bioontology.org/ontology/MESH/C544254 http://purl.bioontology.org/ontology/MESH/C550742 |
| MDA |
19880603 |
| MMR |
20160531 |
| MN |
D02.065.589.099.124.300.500 D03.633.100.300.124.300.500 |
| notation |
D015378 |
| PA |
D000900 |
| prefLabel |
Imipenem |
| RR |
74431-23-5 (Imipenem) Q20IM7HE75 |
| TERMUI |
T045341 T045340 T045342 T045344 T839048 T045343 T359724 |
| TH |
FDA SRS (2014) USP (19XX) UNK (19XX) BAN (19XX) USAN (1983) NLM (2014) NLM (1999) INN (19XX) |
| tui |
T109 T195 T121 |
| subClassOf |