loading...| Preferred Name |
Matrix Metalloproteinase 14 |
| Synonyms |
MMP 14 Metalloproteinase |
| Definitions |
A transmembrane domain-containing matrix metalloproteinase. It is synthesized as an inactive zymogen that is activated by the action of PROPROTEIN CONVERTASES such as FURIN. Matrix metalloproteinase 14 plays a direct role in the cleavage of proteins in the pericellular environment. In addition, it can function indirectly by enzymatically activating the proprotein form of MATRIX METALLOPROTEINASE 15. |
| ID |
http://purl.bioontology.org/ontology/MESH/D053511 |
| altLabel |
MMP 14 Metalloproteinase Metalloproteinase, MMP14 MMP X1 Protein Membrane Type 1 Matrix Metalloproteinase Membrane-Type Matrix Metalloproteinase 1 MMP14 Metalloproteinase Metalloproteinase, MT1-Matrix Membrane Type Matrix Metalloproteinase 1 MT1-Matrix Metalloproteinase Membrane-Type 1 Matrix Metalloproteinase MMP-X1 Protein Metalloproteinase, MMP-14 MMP-14 Metalloproteinase MT1 Matrix Metalloproteinase MT1-MMP Metalloproteinase 14, Matrix MT-MMP-1 |
| AQL |
AD AE AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR |
| cui |
C1618608 |
| DC |
1 |
| definition |
A transmembrane domain-containing matrix metalloproteinase. It is synthesized as an inactive zymogen that is activated by the action of PROPROTEIN CONVERTASES such as FURIN. Matrix metalloproteinase 14 plays a direct role in the cleavage of proteins in the pericellular environment. In addition, it can function indirectly by enzymatically activating the proprotein form of MATRIX METALLOPROTEINASE 15. |
| DX |
20070101 |
| EC |
antagonists & inhibitors:Matrix Metalloproteinase Inhibitors |
| HN |
2007(1994) |
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000528 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000172 |
| Inverse of RB |
EC 3.4.24.80 |
| Machine permutation |
2007; MATRIX METALLOPROTEINASE 14 was indexed under MATRIX METALLOPROTEINASES 2006 & under METALLOENDOPEPTIDASES 1994-2005 |
| Mapped from |
http://purl.bioontology.org/ontology/MESH/C507086 |
| MDA |
20060705 |
| MMR |
20120703 |
| MN |
D08.811.277.656.675.374.525.300.500 D08.811.277.656.300.480.525.300.500 |
| notation |
D053511 |
| prefLabel |
Matrix Metalloproteinase 14 |
| TERMUI |
T262702 T316949 T316951 T316952 T316950 T262708 T642814 T664575 T664593 |
| TH |
NLM (2007) |
| tui |
T116 T126 |
| subClassOf |