Preferred Name |
integrin alpha-X |
Synonyms |
CD11C CD11c leukocyte adhesion receptor p150,95 Leu M5 CD11 antigen-like family member C ITGAX leukocyte adhesion glycoprotein p150,95 alpha chain |
Definitions |
Category=gene. Requested by=CL. An integrin alpha with A domain that is a translation product of the human ITGAX gene or a 1:1 ortholog thereof. Integrin alpha-X complexed with beta-2 is a receptor for fibrinogen. It recognizes the sequence GPR in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. |
ID |
http://purl.obolibrary.org/obo/PR_000001013 |
comment |
Category=gene. Requested by=CL. |
database_cross_reference |
IUPHARobj:2454 |
definition |
An integrin alpha with A domain that is a translation product of the human ITGAX gene or a 1:1 ortholog thereof. Integrin alpha-X complexed with beta-2 is a receptor for fibrinogen. It recognizes the sequence GPR in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. |
has_exact_synonym |
CD11c leukocyte adhesion receptor p150,95 Leu M5 CD11 antigen-like family member C ITGAX leukocyte adhesion glycoprotein p150,95 alpha chain |
has_obo_namespace |
protein |
has_related_synonym |
CD11C |
id |
PR:000001013 |
label |
integrin alpha-X |
notation |
PR:000001013 |
prefLabel |
integrin alpha-X |
subClassOf |