Preferred Name |
prefoldin complex |
Synonyms |
GIM complex |
Definitions |
A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics. |
ID |
http://purl.obolibrary.org/obo/GO_0016272 |
definition |
A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics. |
has_narrow_synonym |
GIM complex |
has_obo_namespace |
cellular_component |
id |
GO:0016272 |
label |
prefoldin complex |
notation |
GO:0016272 |
prefLabel |
prefoldin complex |
treeView | |
subClassOf |
Delete | Mapping To | Ontology | Source |
---|---|---|---|
http://purl.obolibrary.org/obo/GO_0016272 | Gene Ontology / 基因本体 | LOOM | |
http://purl.obolibrary.org/obo/GO_0016272 | Gene Ontology / 基因本体 | SAME_URI |