Preferred Name |
CD3 subunit with immunoglobulin domain |
Synonyms |
CD3 subunit with Ig-like domain |
Definitions |
Category=family. A protein that has a core domain composition consisting of an extracellular N-terminal domain that adopts an immunoglobulin fold, a transmembrane domain, and an intracellular C-terminal domain with a single copy of the Immunoreceptor tyrosine-based activation motif (Pfam:PF02189) (ITAM). It constitutes the invariant subunit of the T cell antigen receptor (TCR). TCR is a surface receptor on T cells responsible for recognizing MHC-restricted antigens and initiating the cellular immune response. |
ID |
http://purl.obolibrary.org/obo/PR_000001018 |
comment |
Category=family. |
database_cross_reference |
PIRSF:PIRSF001993 |
definition |
A protein that has a core domain composition consisting of an extracellular N-terminal domain that adopts an immunoglobulin fold, a transmembrane domain, and an intracellular C-terminal domain with a single copy of the Immunoreceptor tyrosine-based activation motif (Pfam:PF02189) (ITAM). It constitutes the invariant subunit of the T cell antigen receptor (TCR). TCR is a surface receptor on T cells responsible for recognizing MHC-restricted antigens and initiating the cellular immune response. |
has_exact_synonym |
CD3 subunit with Ig-like domain |
has_obo_namespace |
protein |
id |
PR:000001018 |
label |
CD3 subunit with immunoglobulin domain |
notation |
PR:000001018 |
prefLabel |
CD3 subunit with immunoglobulin domain |
treeView | |
subClassOf |