Preferred Name |
Toll-like receptor signaling pathway |
Synonyms |
Toll-Like Receptors Cascades TLR signaling pathway |
Definitions |
Toll-like receptors represent a large and the better understood family of pattern recognition receptors that sense an array of exogenous structures, and recent evidence shows they can also recognize defective endogenous molecules. The intracellular signaling cascades they set in motion lead to the expression of inflammatory mediators. |
ID |
http://purl.obolibrary.org/obo/PW_0000814 |
created_by |
VPetri |
creation_date |
2010-10-27T11:29:27Z |
definition |
Toll-like receptors represent a large and the better understood family of pattern recognition receptors that sense an array of exogenous structures, and recent evidence shows they can also recognize defective endogenous molecules. The intracellular signaling cascades they set in motion lead to the expression of inflammatory mediators. |
has_obo_namespace |
pathway |
has_related_synonym |
Toll-Like Receptors Cascades TLR signaling pathway |
id |
PW:0000814 |
label |
Toll-like receptor signaling pathway |
notation |
PW:0000814 |
prefLabel |
Toll-like receptor signaling pathway |
treeView | |
subClassOf |
Delete | Mapping To | Ontology | Source |
---|---|---|---|
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C91505 | National Cancer Institute Thesaurus / 美国国家癌症研究所词典 | LOOM | |
http://purl.obolibrary.org/obo/GO_0002224 | Gene Ontology / 基因本体 | LOOM |