loading...| Preferred Name |
Receptor, Insulin |
| Synonyms |
Insulin Receptor |
| Definitions |
A cell surface receptor for INSULIN. It comprises a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precursor protein. The receptor contains an intrinsic TYROSINE KINASE domain that is located within the beta subunit. Activation of the receptor by INSULIN results in numerous metabolic changes including increased uptake of GLUCOSE into the liver, muscle, and ADIPOSE TISSUE. |
| ID |
http://purl.bioontology.org/ontology/MESH/D011972 |
| altLabel |
Insulin Receptor Insulin Receptor beta Chain Receptors, Insulin Insulin Receptors Insulin Receptor Protein-Tyrosine Kinase Insulin Receptor alpha Subunit Insulin Receptor alpha Chain Insulin-Dependent Tyrosine Protein Kinase Insulin Receptor beta Subunit Insulin Receptor Protein Tyrosine Kinase |
| AQL |
AD AE AG AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR |
| cui |
C0751464 C0751465 C0034818 |
| DC |
1 |
| definition |
A cell surface receptor for INSULIN. It comprises a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precursor protein. The receptor contains an intrinsic TYROSINE KINASE domain that is located within the beta subunit. Activation of the receptor by INSULIN results in numerous metabolic changes including increased uptake of GLUCOSE into the liver, muscle, and ADIPOSE TISSUE. |
| DX |
19770101 |
| FX |
D056731 |
| HN |
2000(1977); for INSULIN RECEPTOR PROTEIN-TYROSINE KINASE use RECEPTOR, INSULIN (NM) 1983-1993 |
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000528 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000172 |
| Inverse of RB |
0 EC 2.7.10.1 |
| Inverse of RO | |
| Machine permutation |
2000; for INSULIN RECEPTOR PROTEIN-TYROSINE KINASE see INSULIN RECEPTOR PROTEIN-TYROSINE KINASE 1994-1999; INSULIN-DEPENDENT PROTEIN TYROSINE KINASE was indexed under PROTEIN-TYROSINE KINASE 1986-1993 & PROTEIN KINASES 1983-1985 |
| Mapped from |
http://purl.bioontology.org/ontology/MESH/C081827 http://purl.bioontology.org/ontology/MESH/C066542 http://purl.bioontology.org/ontology/MESH/C082834 http://purl.bioontology.org/ontology/MESH/C107483 http://purl.bioontology.org/ontology/MESH/C000629699 http://purl.bioontology.org/ontology/MESH/C051512 http://purl.bioontology.org/ontology/MESH/C029957 http://purl.bioontology.org/ontology/MESH/C435941 http://purl.bioontology.org/ontology/MESH/C102586 |
| MDA |
19760503 |
| MMR |
20210521 |
| MN |
D12.776.543.750.630.484 D12.776.476.568.400.200 D12.776.543.750.750.580.300 D08.811.913.696.620.682.725.400.200 |
| notation |
D011972 |
| prefLabel |
Receptor, Insulin |
| TERMUI |
T053598 T362028 T362027 T362007 T362029 T035530 T362030 T035532 T053603 |
| TH |
NLM (1977) NLM (2000) NLM (1994) |
| tui |
T116 T126 T192 |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.bioontology.org/ontology/LNC/LP18385-2 | Logical Observation Identifier Names and Codes / 逻辑观察标识符名称和代码 | CUI |