loading...| Preferred Name |
macrophage |
| Synonyms |
histiocyte |
| Definitions |
A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells. Morphology: Diameter 30_M-80 _M, abundant cytoplasm, low N/C ratio, eccentric nucleus. Irregular shape with pseudopods, highly adhesive. Contain vacuoles and phagosomes, may contain azurophilic granules; markers: Mouse & Human: CD68, in most cases CD11b. Mouse: in most cases F4/80+; role or process: immune, antigen presentation, & tissue remodelling; lineage: hematopoietic, myeloid. |
| ID |
http://purl.obolibrary.org/obo/CL_0000235 |
| comment |
Morphology: Diameter 30_M-80 _M, abundant cytoplasm, low N/C ratio, eccentric nucleus. Irregular shape with pseudopods, highly adhesive. Contain vacuoles and phagosomes, may contain azurophilic granules; markers: Mouse & Human: CD68, in most cases CD11b. Mouse: in most cases F4/80+; role or process: immune, antigen presentation, & tissue remodelling; lineage: hematopoietic, myeloid. |
| capable of | |
| database_cross_reference |
BTO:0000801 CALOHA:TS-0587 FMA:83585 MESH:D008264 FMA:63261 |
| definition |
A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells. |
| develops_from | |
| has_exact_synonym |
histiocyte |
| in_subset |
http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim |
| label |
macrophage |
| prefixIRI |
CL:0000235 |
| prefLabel |
macrophage |
| present_in_taxon | |
| treeView | |
| subClassOf |
http://purl.obolibrary.org/obo/CL_0000145 |