Preferred Name |
neuroblastoma |
Definitions |
神经母细胞瘤的特征是神经母细胞的出现,神经节细胞的缺失以及没有明显的Schwannian基质形成。 早产儿常见的肿瘤来源于交感神经系统的神经嵴细胞,具有不同的临床表现,从自发缓解到快速转移进展和死亡。这种肿瘤是儿童时期最常见的腹腔内恶性肿瘤,但也可能起源于胸部,颈部或罕见的中枢神经系统。组织学特征包括均匀的圆形细胞,在巢中排列有多色核,并通过纤维血管间隔分开。神经母细胞瘤可能与眼球阵挛-肌阵挛综合征(MeSH)有关。(DeVita等人,Cancer:Principles and Practice of Oncology,5th ed,pp2099-2101; Curr Opin Oncol 1998 Jan; 10(1):43-51) 早产儿常见的肿瘤来源于交感神经系统的神经嵴细胞,具有不同的临床表现,从自发缓解到快速转移进展和死亡。这种肿瘤是儿童时期最常见的腹腔内恶性肿瘤,但也可能起源于胸部,颈部或罕见的中枢神经系统。组织学特征包括均匀的圆形细胞,在巢中排列有多色核,并通过纤维血管间隔分开。神经母细胞瘤可能与眼球阵挛-肌阵挛综合征(MeSH)有关。 A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51) |
ID |
http://www.ebi.ac.uk/efo/EFO_0000621 |
comment |
神经母细胞瘤的特征是神经母细胞的出现,神经节细胞的缺失以及没有明显的Schwannian基质形成。 早产儿常见的肿瘤来源于交感神经系统的神经嵴细胞,具有不同的临床表现,从自发缓解到快速转移进展和死亡。这种肿瘤是儿童时期最常见的腹腔内恶性肿瘤,但也可能起源于胸部,颈部或罕见的中枢神经系统。组织学特征包括均匀的圆形细胞,在巢中排列有多色核,并通过纤维血管间隔分开。神经母细胞瘤可能与眼球阵挛-肌阵挛综合征(MeSH)有关。(DeVita等人,Cancer:Principles and Practice of Oncology,5th ed,pp2099-2101; Curr Opin Oncol 1998 Jan; 10(1):43-51) 早产儿常见的肿瘤来源于交感神经系统的神经嵴细胞,具有不同的临床表现,从自发缓解到快速转移进展和死亡。这种肿瘤是儿童时期最常见的腹腔内恶性肿瘤,但也可能起源于胸部,颈部或罕见的中枢神经系统。组织学特征包括均匀的圆形细胞,在巢中排列有多色核,并通过纤维血管间隔分开。神经母细胞瘤可能与眼球阵挛-肌阵挛综合征(MeSH)有关。 A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51) A neuroblastic tumor characterized by the presence of neuroblastic cells, the absence of ganglion cells, and the absence of a prominent Schwannian stroma formation. A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome (MeSH). |
definition source |
GeneRIF:11737230 GeneRIF:12557224 GeneRIF:12118090 GeneRIF:14988008 GeneRIF:11782392 GeneRIF:15328517 GeneRIF:15994346 GeneRIF:15448191 GeneRIF:15644444 GeneRIF:15998644 GeneRIF:12675130 GeneRIF:15117961 GeneRIF:15882878 GeneRIF:15930276 GeneRIF:14654552 GeneRIF:12185581 GeneRIF:12808116 GeneRIF:12962147 GeneRIF:15547663 GeneRIF:15827327 GeneRIF:12576454 GeneRIF:15607966 GeneRIF:16092940 GeneRIF:14719101 GeneRIF:12629521 GeneRIF:16051641 GeneRIF:15618969 GeneRIF:16007146 SNOMEDCT:269507008 GeneRIF:12239177 NIFSTD:birnlex_12631 GeneRIF:15719172 GeneRIF:15280446 GeneRIF:14663483 GeneRIF:12545167 GeneRIF:16166307 GeneRIF:15024693 SNOMEDCT:87364003 GeneRIF:11744098 GeneRIF:14745549 GeneRIF:12163469 GeneRIF:12916719 GeneRIF:12647219 GeneRIF:12154078 GeneRIF:15316056 GeneRIF:16177824 GeneRIF:11705866 GeneRIF:15486895 GeneRIF:15516980 GeneRIF:15741235 MSH:D009447 GeneRIF:12209604 DOID:769 GeneRIF:11859407 GeneRIF:11877670 GeneRIF:15488758 GeneRIF:15218241 GeneRIF:15240516 GeneRIF:16125842 GeneRIF:11928813 GeneRIF:11807986 GeneRIF:15136145 GeneRIF:16091745 GeneRIF:11881792 GeneRIF:15015775 GeneRIF:16232196 GeneRIF:15166121 GeneRIF:15735700 GeneRIF:11877677 GeneRIF:12593854 GeneRIF:16228012 GeneRIF:12717420 GeneRIF:15514946 GeneRIF:12085233 GeneRIF:15650242 GeneRIF:12884264 GeneRIF:15168079 GeneRIF:11870543 GeneRIF:12964007 GeneRIF:15849504 GeneRIF:11861392 GeneRIF:13679866 GeneRIF:15004408 GeneRIF:15322424 GeneRIF:12174591 GeneRIF:15375504 GeneRIF:12888911 GeneRIF:12031683 GeneRIF:11836564 GeneRIF:12438307 GeneRIF:14995074 NCIt:C3270 GeneRIF:16098972 GeneRIF:12672031 GeneRIF:14645238 GeneRIF:12829373 GeneRIF:15518890 GeneRIF:12907629 GeneRIF:14724587 GeneRIF:12598334 GeneRIF:15083193 GeneRIF:12629151 |
label |
neuroblastoma 神经母细胞瘤 |
prefixIRI |
efo:EFO_0000621 |
prefLabel |
neuroblastoma |
seeAlso | |
引自 | |
替代术语 |
神经母细胞瘤 (Schwannian Stroma-Poor) neuroblastoma NOS (morphologic abnormality) NB-神经母细胞瘤 (Neuroblastoma NOS) or (sympathicoblastoma) (成神经细胞瘤NOS)或(交感神经细胞瘤) 神经母细胞瘤NOS(形态异常) 神经母细胞瘤,NOS [M]Neuroblastoma NOS 神经母细胞瘤(Neuroblastomas) 成神经细胞瘤(形态异常) Central neuroblastoma 中枢神经母细胞瘤 neuroblastoma Sympathicoblastoma [M]Neuroblastoma NOS (morphologic abnormality) 成交感神经细胞瘤 Neuroblastoma, NOS 神经母细胞瘤 NB - Neuroblastoma Neuroblastomas [M]神经母细胞瘤NOS(形态异常) Neuroblastoma (Schwannian Stroma-Poor) [M]神经母细胞瘤NOS neuroblastoma (morphologic abnormality) |
术语编辑者 |
James Malone Tomasz Adamusiak |
subClassOf |