Preferred Name

neuroblastoma

Definitions

神经母细胞瘤的特征是神经母细胞的出现,神经节细胞的缺失以及没有明显的Schwannian基质形成。 早产儿常见的肿瘤来源于交感神经系统的神经嵴细胞,具有不同的临床表现,从自发缓解到快速转移进展和死亡。这种肿瘤是儿童时期最常见的腹腔内恶性肿瘤,但也可能起源于胸部,颈部或罕见的中枢神经系统。组织学特征包括均匀的圆形细胞,在巢中排列有多色核,并通过纤维血管间隔分开。神经母细胞瘤可能与眼球阵挛-肌阵挛综合征(MeSH)有关。(DeVita等人,Cancer:Principles and Practice of Oncology,5th ed,pp2099-2101; Curr Opin Oncol 1998 Jan; 10(1):43-51) 早产儿常见的肿瘤来源于交感神经系统的神经嵴细胞,具有不同的临床表现,从自发缓解到快速转移进展和死亡。这种肿瘤是儿童时期最常见的腹腔内恶性肿瘤,但也可能起源于胸部,颈部或罕见的中枢神经系统。组织学特征包括均匀的圆形细胞,在巢中排列有多色核,并通过纤维血管间隔分开。神经母细胞瘤可能与眼球阵挛-肌阵挛综合征(MeSH)有关。 A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

ID

http://www.ebi.ac.uk/efo/EFO_0000621

comment

神经母细胞瘤的特征是神经母细胞的出现,神经节细胞的缺失以及没有明显的Schwannian基质形成。

早产儿常见的肿瘤来源于交感神经系统的神经嵴细胞,具有不同的临床表现,从自发缓解到快速转移进展和死亡。这种肿瘤是儿童时期最常见的腹腔内恶性肿瘤,但也可能起源于胸部,颈部或罕见的中枢神经系统。组织学特征包括均匀的圆形细胞,在巢中排列有多色核,并通过纤维血管间隔分开。神经母细胞瘤可能与眼球阵挛-肌阵挛综合征(MeSH)有关。(DeVita等人,Cancer:Principles and Practice of Oncology,5th ed,pp2099-2101; Curr Opin Oncol 1998 Jan; 10(1):43-51)

早产儿常见的肿瘤来源于交感神经系统的神经嵴细胞,具有不同的临床表现,从自发缓解到快速转移进展和死亡。这种肿瘤是儿童时期最常见的腹腔内恶性肿瘤,但也可能起源于胸部,颈部或罕见的中枢神经系统。组织学特征包括均匀的圆形细胞,在巢中排列有多色核,并通过纤维血管间隔分开。神经母细胞瘤可能与眼球阵挛-肌阵挛综合征(MeSH)有关。

A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

A neuroblastic tumor characterized by the presence of neuroblastic cells, the absence of ganglion cells, and the absence of a prominent Schwannian stroma formation.

A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome (MeSH).

definition source

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label

neuroblastoma

神经母细胞瘤

prefixIRI

efo:EFO_0000621

prefLabel

neuroblastoma

seeAlso

URI: http://www.ebi.ac.uk/cellline#neuroblastoma

引自

http://purl.obolibrary.org/obo/clo.owl

替代术语

神经母细胞瘤 (Schwannian Stroma-Poor)

neuroblastoma NOS (morphologic abnormality)

NB-神经母细胞瘤

(Neuroblastoma NOS) or (sympathicoblastoma)

(成神经细胞瘤NOS)或(交感神经细胞瘤)

神经母细胞瘤NOS(形态异常)

神经母细胞瘤,NOS

[M]Neuroblastoma NOS

神经母细胞瘤(Neuroblastomas)

成神经细胞瘤(形态异常)

Central neuroblastoma

中枢神经母细胞瘤

neuroblastoma

Sympathicoblastoma

[M]Neuroblastoma NOS (morphologic abnormality)

成交感神经细胞瘤

Neuroblastoma, NOS

神经母细胞瘤

NB - Neuroblastoma

Neuroblastomas

[M]神经母细胞瘤NOS(形态异常)

Neuroblastoma (Schwannian Stroma-Poor)

[M]神经母细胞瘤NOS

neuroblastoma (morphologic abnormality)

术语编辑者

James Malone

Tomasz Adamusiak

subClassOf

http://purl.obolibrary.org/obo/DOID_2622

http://purl.obolibrary.org/obo/DOID_4158

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Delete Mapping To Ontology Source
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3270 National Cancer Institute Thesaurus / 美国国家癌症研究所词典 LOOM
http://www.ebi.ac.uk/efo/EFO_0000621 细胞系本体(中文翻译) / Cell Line Ontology (Chinese Translation) SAME_URI
http://www.ebi.ac.uk/efo/EFO_0000621 Experimental Factor Ontology / 实验性因素本体 LOOM
http://www.ebi.ac.uk/efo/EFO_0000621 Experimental Factor Ontology / 实验性因素本体 SAME_URI
http://purl.obolibrary.org/obo/NCIT_C3270 中国人类表型本体 / Human Phenotype Ontology China LOOM
http://purl.obolibrary.org/obo/MONDO_0005072 Mondo Disease Ontology / Mondo疾病本体 LOOM
http://purl.bioontology.org/ontology/OMIM/MTHU013400 Online Mendelian Inheritance in Man / 在线人类孟德尔遗传数据库 LOOM
http://www.orpha.net/ORDO/Orphanet_635 Orphanet Rare Disease Ontology / Orphanet罕见病本体 LOOM
http://purl.obolibrary.org/obo/DOID_769 BioAssay Ontology / 生物活性分析本体 LOOM
http://purl.obolibrary.org/obo/DOID_769 Human Disease Ontology / 人类疾病本体 LOOM
http://purl.bioontology.org/ontology/MEDLINEPLUS/C0027819 MedlinePlus Health Topics / MedlinePlus网站健康主题 LOOM
http://purl.obolibrary.org/obo/MPATH_376 中国人类表型本体 / Human Phenotype Ontology China LOOM
http://purl.obolibrary.org/obo/HP_0003006 Human Phenotype Ontology / 人类表型本体 LOOM
http://purl.bioontology.org/ontology/MESH/D009447 Medical Subject Headings / 医学主题词表 LOOM