Human Phenotype Ontology / 人类表型本体

Last uploaded: September 7, 2023
Preferred Name

Gangrene

Synonyms

Death of body tissue due to lack of blood flow or infection

Definitions

This may occur after an injury or infection, or in people suffering from any chronic health problem affecting blood circulation. The prime cause of gangrene is reduced blood supply to the affected tissues, which results in cell death. Diabetes and long-term smoking increase the risk of suffering from gangrene. There are different types of gangrene with different symptoms, such as dry gangrene, wet gangrene, gas gangrene, internal gangrene and necrotising fasciitis. Treatment options include debridement (or, in severe cases, amputation) of the affected body parts, antibiotics, vascular surgery, maggot therapy or hyperbaric oxygen therapy. A serious and potentially life-threatening condition that arises when a considerable mass of body tissue dies (necrosis).

ID

http://purl.obolibrary.org/obo/HP_0100758

comment

This may occur after an injury or infection, or in people suffering from any chronic health problem affecting blood circulation. The prime cause of gangrene is reduced blood supply to the affected tissues, which results in cell death. Diabetes and long-term smoking increase the risk of suffering from gangrene. There are different types of gangrene with different symptoms, such as dry gangrene, wet gangrene, gas gangrene, internal gangrene and necrotising fasciitis. Treatment options include debridement (or, in severe cases, amputation) of the affected body parts, antibiotics, vascular surgery, maggot therapy or hyperbaric oxygen therapy.

creation_date

2011-06-07T10:19:11Z

creator

https://orcid.org/0009-0006-4530-3154

database_cross_reference

MSH:D005734

SNOMEDCT_US:372070002

UMLS:C0017086

SNOMEDCT_US:36024000

definition

A serious and potentially life-threatening condition that arises when a considerable mass of body tissue dies (necrosis).

has_exact_synonym

Death of body tissue due to lack of blood flow or infection

has_obo_namespace

human_phenotype

id

HP:0100758

label

Gangrene

notation

HP:0100758

prefLabel

Gangrene

treeView

http://purl.obolibrary.org/obo/HP_0025142

subClassOf

http://purl.obolibrary.org/obo/HP_0025142

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