loading...| Preferred Name |
blood island |
| Synonyms |
blood islands caudal hematopoietic tissue posterior blood island ventral blood island ventral lateral plate mesoderm VBI posterior ICM |
| Definitions |
Blood islands are structures in the developing embryo which lead to many different parts of the circulatory system. They primarily derive from plexuses formed from angioblasts. Within them, vacuoles appear through liquefaction of the central part of the syncytium into plasma. The lumen of the blood vessels thus formed is probably intracellular. The flattened cells at the periphery form the endothelium. The nucleated red blood corpuscles develop either from small masses of the original angioblast left attached to the inner wall of the lumen or directly from the flat endothelial cells. In either case the syncytial mass thus formed projects from and is attached to the wall of the vessel. Such a mass is known as a blood island and hemoglobin gradually accumulates within it. Later the cells on the surface round up, giving the mass a mulberry-like appearance. Then the red blood cells break loose and are carried away in the plasma. Such free blood cells continue to divide. Blood islands have been seen in the area vasculosa in the omphalomesenteric vein and arteries, and in the dorsal aorta[WP, unvetted]. |
| ID |
http://purl.obolibrary.org/obo/UBERON_0003061 |
| axiom_lost_from_external_ontology |
relationship loss: part_of intermediate cell mass of mesoderm (TAO:0000033)[TAO] |
| database_cross_reference |
TAO:0000094 EFO:0003489 XAO:0000067 ZFA:0000094 EHDAA:207 AAO:0011006 UMLS:C1511224 VHOG:0000085 TE:E5.11.2.0.0.0.4 http://en.wikipedia.org/wiki/Blood_island_of_umbilical_vesicle |
| develops_from | |
| external_definition |
Region located on the ventral surface of the developing embryo that is a site of hematopoiesis and that is analogous to the yolk sac blood islands of higher vertebrates.[AAO] Nests of developing blood cells arising late in the segmentation period from the intermediate mass, and located in the anterior-ventral tail, just posterior to the yolk extension. Kimmel et al, 1995.[TAO] |
| external_ontology_notes |
EHDAA2 distinguishes 3 types, but does not have a superclass. The VHOG class may refer to yolk sac |
| has exact synonym |
blood islands |
| has potential to develop into | |
| has_broad_synonym |
ventral lateral plate mesoderm |
| has_obo_namespace |
uberon |
| has_related_synonym |
caudal hematopoietic tissue posterior blood island ventral blood island VBI posterior ICM |
| homology_notes |
Small clusters of mesodermal cells called blood islands mark the embryonic debut of the cardiovascular system (in vertebrates) (reference 1); In birds and mammals, primitive hemangioblasts are extraembryonic, populating the yolk sac as the so-called blood islands (reference 2).[well established][VHOG] |
| id |
UBERON:0003061 |
| imported from | |
| in_subset |
http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#uberon_slim http://purl.oboInOwllibrary.org/oboInOwl/uberon#uberon_slim http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#pheno_slim http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#vertebrate_core http://purl.oboInOwllibrary.org/oboInOwl/uberon#vertebrate_core http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#efo_slim |
| label |
blood island |
| notation |
UBERON:0003061 |
| part_of | |
| prefLabel |
blood island |
| textual definition |
Blood islands are structures in the developing embryo which lead to many different parts of the circulatory system. They primarily derive from plexuses formed from angioblasts. Within them, vacuoles appear through liquefaction of the central part of the syncytium into plasma. The lumen of the blood vessels thus formed is probably intracellular. The flattened cells at the periphery form the endothelium. The nucleated red blood corpuscles develop either from small masses of the original angioblast left attached to the inner wall of the lumen or directly from the flat endothelial cells. In either case the syncytial mass thus formed projects from and is attached to the wall of the vessel. Such a mass is known as a blood island and hemoglobin gradually accumulates within it. Later the cells on the surface round up, giving the mass a mulberry-like appearance. Then the red blood cells break loose and are carried away in the plasma. Such free blood cells continue to divide. Blood islands have been seen in the area vasculosa in the omphalomesenteric vein and arteries, and in the dorsal aorta[WP, unvetted]. |
| treeView | |
| subClassOf |