Preferred Name

Aplastic Anemia

Definitions

<h3>What is aplastic anemia?</h3> <p>Aplastic <a href="https://medlineplus.gov/anemia.html"> anemia</a> is a rare but serious blood disorder. If you have it, your <a href="https://medlineplus.gov/bonemarrowdiseases.html">bone marrow</a> doesn't make enough new blood cells. It happens when there is damage to stem cells inside your bone marrow. There are different types of aplastic anemia, including Fanconi anemia.</p> <h3>What causes aplastic anemia?</h3> <p>The causes of aplastic anemia can include:</p> <ul> <li><a href="https://medlineplus.gov/autoimmunediseases.html">Autoimmune disorders</a>, which are the most common cause</li> <li>Certain inherited gene changes, such as <a href="https://medlineplus.gov/genetics/condition/fanconi-anemia/">the one that can cause Fanconi anemia</a></li> <li>Toxic substances, such as <a href="https://medlineplus.gov/pesticides.html">pesticides</a>, <a href="https://medlineplus.gov/arsenic.html">arsenic</a>, and benzene</li> <li><a href="https://medlineplus.gov/radiationtherapy.html">Radiation therapy</a> and <a href="https://medlineplus.gov/cancerchemotherapy.html">chemotherapy</a> for cancer</li> <li>Certain medicines</li> <li>Viral infections such as <a href="https://medlineplus.gov/hepatitis.html">hepatitis</a>, Epstein-Barr virus, or <a href="https://medlineplus.gov/hivaids.html">HIV</a></li> <li>Pregnancy</li> </ul> <p>In many people, the cause is unknown. This is called idiopathic aplastic anemia.</p> <h3>What are the symptoms of aplastic anemia?</h3> <p>Aplastic anemia can develop suddenly or slowly. It can be mild or severe. The symptoms of aplastic anemia can include:</p> <ul> <li><a href="https://medlineplus.gov/fatigue.html">Fatigue</a></li> <li>Weakness</li> <li><a href="https://medlineplus.gov/dizzinessandvertigo.html">Dizziness</a></li> <li><a href="https://medlineplus.gov/breathingproblems.html">Shortness of breath</a></li> <li>Easy <a href="https://medlineplus.gov/bruises.html">bruising</a> or <a href="https://medlineplus.gov/bleeding.html">bleeding</a></li> </ul> <h3>What other problems can aplastic anemia cause?</h3> <p>Aplastic anemia can cause other problems, including frequent infections and bleeding. It raises your risk of developing a serious <a href="https://medlineplus.gov/blooddisorders.html">blood disorder</a>.</p> <p>If not treated, aplastic anemia can also lead to heart problems such as an <a href="https://medlineplus.gov/arrhythmia.html">arrhythmia</a> (a problem with the rate or rhythm of your heartbeat), an enlarged heart, or <a href="https://medlineplus.gov/heartfailure.html">heart failure</a>.</p> <h3>How is aplastic anemia diagnosed?</h3> <p>To find out if you have aplastic anemia, your doctor will:</p><p> </p><ul> <li>Take your medical and your family medical histories</li> <li>Do a physical exam</li> <li>Order tests, such as tests to check if you have low numbers of cells in your bone marrow and blood</li> </ul> <h3>What are the treatments for aplastic anemia?</h3> <p>If you have aplastic anemia, your doctor will create a treatment plan for you. The plan will be based on how severe the anemia is and what is causing it. Treatments can include:</p> <ul> <li>Blood <a href="https://medlineplus.gov/bloodtransfusionanddonation.html">transfusions</a></li> <li>Blood and marrow <a href="https://medlineplus.gov/stemcells.html">stem cell transplants</a></li> <li>Medicines to suppress your immune system</li> </ul> <p>Because of the risk of blood disorders, your doctor will monitor your condition and screen you for blood disorders regularly.</p> <p class="">NIH: National Heart, Lung, and Blood Institute</p>

ID

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0002874

cui

C0002874

Date created

01/04/2012

definition

What is aplastic anemia?

Aplastic anemia is a rare but serious blood disorder. If you have it, your bone marrow doesn't make enough new blood cells. It happens when there is damage to stem cells inside your bone marrow. There are different types of aplastic anemia, including Fanconi anemia.

What causes aplastic anemia?

The causes of aplastic anemia can include:

In many people, the cause is unknown. This is called idiopathic aplastic anemia.

What are the symptoms of aplastic anemia?

Aplastic anemia can develop suddenly or slowly. It can be mild or severe. The symptoms of aplastic anemia can include:

What other problems can aplastic anemia cause?

Aplastic anemia can cause other problems, including frequent infections and bleeding. It raises your risk of developing a serious blood disorder.

If not treated, aplastic anemia can also lead to heart problems such as an arrhythmia (a problem with the rate or rhythm of your heartbeat), an enlarged heart, or heart failure.

How is aplastic anemia diagnosed?

To find out if you have aplastic anemia, your doctor will:

  • Take your medical and your family medical histories
  • Do a physical exam
  • Order tests, such as tests to check if you have low numbers of cells in your bone marrow and blood

What are the treatments for aplastic anemia?

If you have aplastic anemia, your doctor will create a treatment plan for you. The plan will be based on how severe the anemia is and what is causing it. Treatments can include:

Because of the risk of blood disorders, your doctor will monitor your condition and screen you for blood disorders regularly.

NIH: National Heart, Lung, and Blood Institute

Inverse of RQ

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0015625

Mapped from

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0002874

Mapped to

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0002874

MP OTHER LANGUAGE URL

Spanish https://medlineplus.gov/spanish/aplasticanemia.html

MP PRIMARY INSTITUTE URL

National Heart, Lung, and Blood Institute http://www.nhlbi.nih.gov/

notation

C0002874

prefLabel

Aplastic Anemia

Related to

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0002871

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0005956

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0005961

Scope Statement

Aplastic anemia is a rare but serious blood disorder. If you have it, your bone marrow doesn't make enough new blood cells. Read more on the causes. https://medlineplus.gov/aplasticanemia.html

tui

T047

subClassOf

http://purl.bioontology.org/ontology/MEDLINEPLUS/C2362499

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0020962

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http://purl.bioontology.org/ontology/OMIM/602667 Online Mendelian Inheritance in Man / 在线人类孟德尔遗传数据库 CUI
http://purl.obolibrary.org/obo/HP_0001915 Experimental Factor Ontology / 实验性因素本体 LOOM
http://purl.obolibrary.org/obo/HP_0001915 Human Phenotype Ontology / 人类表型本体 LOOM
http://purl.bioontology.org/ontology/OMIM/170280 Online Mendelian Inheritance in Man / 在线人类孟德尔遗传数据库 CUI
http://purl.bioontology.org/ontology/ICD10CM/D61.9 International Classification of Diseases, Version 10 - Clinical Modification / 国际疾病分类,第10版-临床修改 CUI
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2870 National Cancer Institute Thesaurus / 美国国家癌症研究所词典 LOOM
http://purl.bmicc.cn/ontology/ICD10CN/D61.9 《国际疾病分类》第10版中文版 / International Classification of Diseases, 10th Edition, China CUI
http://purl.bioontology.org/ontology/MESH/D000741 Medical Subject Headings / 医学主题词表 CUI
http://purl.obolibrary.org/obo/DOID_12449 BioAssay Ontology / 生物活性分析本体 LOOM
http://purl.obolibrary.org/obo/DOID_12449 Human Disease Ontology / 人类疾病本体 LOOM
http://purl.bioontology.org/ontology/OMIM/609135 Online Mendelian Inheritance in Man / 在线人类孟德尔遗传数据库 CUI
http://purl.bioontology.org/ontology/OMIM/609135 Online Mendelian Inheritance in Man / 在线人类孟德尔遗传数据库 LOOM
http://purl.bioontology.org/ontology/ICD10/D61.9 International Classification of Diseases, Version 10 / 《国际疾病分类》第10版 CUI
http://purl.obolibrary.org/obo/MONDO_0015909 Mondo Disease Ontology / Mondo疾病本体 LOOM
http://purl.obolibrary.org/obo/MONDO_0015909 Experimental Factor Ontology / 实验性因素本体 LOOM
http://purl.bioontology.org/ontology/OMIM/MTHU009662 Online Mendelian Inheritance in Man / 在线人类孟德尔遗传数据库 CUI
http://purl.bioontology.org/ontology/OMIM/MTHU009662 Online Mendelian Inheritance in Man / 在线人类孟德尔遗传数据库 LOOM