Preferred Name

Scleroderma

Synonyms

Dermatosclerosis

Definitions

<p>Scleroderma means hard skin. It is a group of diseases that cause abnormal growth of connective tissue. Connective tissue is the material inside your body that gives your tissues their shape and helps keep them strong. In scleroderma, the tissue gets hard or thick. It can cause swelling or pain in your muscles and joints.</p> <p>Symptoms of scleroderma include :</p><ul> <li> Calcium deposits in connective tissues</li> <li> <a href="https://medlineplus.gov/raynaudsdisease.html">Raynaud's phenomenon</a>, a narrowing of blood vessels in the hands or feet</li> <li> Swelling of the esophagus, the tube between your throat and stomach</li> <li> Thick, tight skin on your fingers</li> <li> Red spots on your hands and face </li> </ul> <p>No one knows what causes scleroderma. It is more common in women. It can be mild or severe. Doctors diagnose scleroderma using your medical history, a physical exam, lab tests, and a skin biopsy. There is no cure, but various treatments can control symptoms and complications. </p> <p class="">NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases</p>

ID

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0011644

altLabel

Dermatosclerosis

cui

C0011644

Date created

10/01/1999

definition

Scleroderma means hard skin. It is a group of diseases that cause abnormal growth of connective tissue. Connective tissue is the material inside your body that gives your tissues their shape and helps keep them strong. In scleroderma, the tissue gets hard or thick. It can cause swelling or pain in your muscles and joints.

Symptoms of scleroderma include :

  • Calcium deposits in connective tissues
  • Raynaud's phenomenon, a narrowing of blood vessels in the hands or feet
  • Swelling of the esophagus, the tube between your throat and stomach
  • Thick, tight skin on your fingers
  • Red spots on your hands and face

No one knows what causes scleroderma. It is more common in women. It can be mild or severe. Doctors diagnose scleroderma using your medical history, a physical exam, lab tests, and a skin biopsy. There is no cure, but various treatments can control symptoms and complications.

NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases

Inverse of RQ

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0036421

http://purl.bioontology.org/ontology/MEDLINEPLUS/C1527383

Inverse of SY

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0036421

http://purl.bioontology.org/ontology/MEDLINEPLUS/C1527383

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0011644

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0036420

Mapped to

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0036421

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0036420

MP OTHER LANGUAGE URL

Spanish https://medlineplus.gov/spanish/scleroderma.html

MP PRIMARY INSTITUTE URL

National Institute of Arthritis and Musculoskeletal and Skin Diseases http://www.niams.nih.gov/

notation

C0011644

prefLabel

Scleroderma

Related to

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0037274

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0034734

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0009782

Scope Statement

Scleroderma is a group of diseases that cause abnormal growth of connective tissue (such as morphea, systemic sclerosis, CREST syndrome). Learn more.https://medlineplus.gov/scleroderma.html

tui

T047

subClassOf

http://purl.bioontology.org/ontology/MEDLINEPLUS/C1456601

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0020962

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/DOID_419 BioAssay Ontology / 生物活性分析本体 LOOM
http://purl.obolibrary.org/obo/DOID_419 Human Disease Ontology / 人类疾病本体 LOOM
http://purl.obolibrary.org/obo/HP_0100324 Human Phenotype Ontology / 人类表型本体 LOOM
http://purl.bioontology.org/ontology/MESH/D012594 Medical Subject Headings / 医学主题词表 CUI
http://www.orpha.net/ORDO/Orphanet_801 Orphanet Rare Disease Ontology / Orphanet罕见病本体 LOOM
http://purl.bioontology.org/ontology/LNC/LA15306-6 Logical Observation Identifier Names and Codes / 逻辑观察标识符名称和代码 CUI
http://purl.bioontology.org/ontology/LNC/LA15306-6 Logical Observation Identifier Names and Codes / 逻辑观察标识符名称和代码 LOOM
http://purl.bioontology.org/ontology/NCBITAXON/68787 National Center for Biotechnology Information (NCBI) Organismal Classification / 美国国家生物技术信息中心(NCBI)生物分类 LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26746 National Cancer Institute Thesaurus / 美国国家癌症研究所词典 LOOM
http://purl.bioontology.org/ontology/OMIM/MTHU010137 Online Mendelian Inheritance in Man / 在线人类孟德尔遗传数据库 CUI
http://purl.bioontology.org/ontology/OMIM/MTHU010137 Online Mendelian Inheritance in Man / 在线人类孟德尔遗传数据库 LOOM
http://purl.obolibrary.org/obo/MONDO_0019340 Mondo Disease Ontology / Mondo疾病本体 LOOM
http://www.ebi.ac.uk/efo/EFO_1001993 Experimental Factor Ontology / 实验性因素本体 LOOM