| Definitions |
A 21-amino acid peptide produced in a variety of tissues including endothelial and vascular smooth-muscle cells, neurons and astrocytes in the central nervous system, and endometrial cells. It acts as a modulator of vasomotor tone, cell proliferation, and hormone production. (N Eng J Med 1995;333(6):356-63)
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| altLabel |
Big Endothelin-1 Precursor, Proendothelin-1 Proendothelin 1 Precursor Preproendothelin-1 Endothelin, Big Proendothelin (1-38) Preproendothelin Endothelin 1 Big Endothelin 1 Big Endothelin Proendothelin-1 Precursor Endothelin Type 1 Endothelin-1, Big Preproendothelin 1
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| definition |
A 21-amino acid peptide produced in a variety of tissues including endothelial and vascular smooth-muscle cells, neurons and astrocytes in the central nervous system, and endometrial cells. It acts as a modulator of vasomotor tone, cell proliferation, and hormone production. (N Eng J Med 1995;333(6):356-63) A 38 amino acid form of endothelin-1 that results from alternative processing of proendothelin-1.
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