Medical Subject Headings / 医学主题词表

Last uploaded: September 7, 2023

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Preferred Name	Leptin
Synonyms	Gene Product, Ob
Definitions	A 16-kDa peptide hormone secreted from WHITE ADIPOCYTES. Leptin serves as a feedback signal from fat cells to the CENTRAL NERVOUS SYSTEM in regulation of food intake, energy balance, and fat storage.
ID	http://purl.bioontology.org/ontology/MESH/D020738
altLabel	Gene Product, Ob Gene Product, Obese Ob Gene Product Ob Protein Obese Protein Obese Gene Product
AQL	AA AD AE AG AI AN BI BL CF CH CL CS DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UR
cui	C0299583
DC	1
definition	A 16-kDa peptide hormone secreted from WHITE ADIPOCYTES. Leptin serves as a feedback signal from fat cells to the CENTRAL NERVOUS SYSTEM in regulation of food intake, energy balance, and fat storage.
DX	20000101
HN	2000; use LEPTIN (NM) 1995-1999
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000528 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627
Inverse of RB	0
Machine permutation	2000; OB PROTEIN (now LEPTIN) was indexed under PROTEINS 1995-1999
Mapped from	http://purl.bioontology.org/ontology/MESH/C549021 http://purl.bioontology.org/ontology/MESH/C487164 http://purl.bioontology.org/ontology/MESH/C000630546 http://purl.bioontology.org/ontology/MESH/C410793 http://purl.bioontology.org/ontology/MESH/C415771 http://purl.bioontology.org/ontology/MESH/C581199 http://purl.bioontology.org/ontology/MESH/C484843 http://purl.bioontology.org/ontology/MESH/C487163 http://purl.bioontology.org/ontology/MESH/C521086 http://purl.bioontology.org/ontology/MESH/C418217 http://purl.bioontology.org/ontology/MESH/C000629008 http://purl.bioontology.org/ontology/MESH/C122136
MDA	19991103
MMR	20070709
MN	D12.776.467.024.500 D23.529.024.500 D12.644.276.024.500 D12.644.548.011.500 D06.472.699.042.500
notation	D020738
prefLabel	Leptin
TERMUI	T279124 T279126 T279125 T279127 T279123
TH	NLM (2000)
tui	T125 T116
subClassOf	http://purl.bioontology.org/ontology/MESH/D054392

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Mapping To	Ontology	Source
http://purl.obolibrary.org/obo/PR_000009758	Protein Ontology / 蛋白质本体	LOOM
http://purl.obolibrary.org/obo/PR_000009758	中国人类表型本体 / Human Phenotype Ontology China	LOOM
http://purl.obolibrary.org/obo/PR_000009758	Ontology for Biomedical Investigations / 生物医学研究本体	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU009760	Logical Observation Identifier Names and Codes / 逻辑观察标识符名称和代码	CUI
http://purl.bioontology.org/ontology/LNC/MTHU009760	Logical Observation Identifier Names and Codes / 逻辑观察标识符名称和代码	LOOM
http://purl.bioontology.org/ontology/OMIM/164160	Online Mendelian Inheritance in Man / 在线人类孟德尔遗传数据库	LOOM
http://purl.obolibrary.org/obo/CHEBI_81571	Chemical Entities of Biological Interest Ontology / 生物相关的化学实体本体	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C46081	National Cancer Institute Thesaurus / 美国国家癌症研究所词典	LOOM
http://www.ebi.ac.uk/efo/EFO_0003199	Experimental Factor Ontology / 实验性因素本体	LOOM
http://www.orpha.net/ORDO/Orphanet_123034	Orphanet Rare Disease Ontology / Orphanet罕见病本体	LOOM
http://purl.bioontology.org/ontology/LNC/LP19488-3	Logical Observation Identifier Names and Codes / 逻辑观察标识符名称和代码	CUI
http://purl.bioontology.org/ontology/LNC/LP19488-3	Logical Observation Identifier Names and Codes / 逻辑观察标识符名称和代码	LOOM