Preferred Name

mast cell progenitor

Synonyms

MCP

colony forming unit mast cell

CFU-MC

CFU-Mast

Definitions

MCP are CD16-positive, CD32-positive, CD34-positive, CD45-positive, integrin beta-7-positive, and lin-negative (CD2, CD3e, CD4, CD5, CD8a, CD14, CD19, CD20, CD27, integrin alpha-M, ly6c, ly6g, NCAM-1, and ter119). These cells also express the transcription factors GATA-1, GATA-2, and MITF, but not C/EBPa. A progenitor cell of the mast cell lineage. Markers for this cell are FceRIa-low, CD117-positive, CD9-positive, T1/ST2-positive, SCA1-negative, and lineage-negative.

ID

http://purl.obolibrary.org/obo/CL_0000831

comment

MCP are CD16-positive, CD32-positive, CD34-positive, CD45-positive, integrin beta-7-positive, and lin-negative (CD2, CD3e, CD4, CD5, CD8a, CD14, CD19, CD20, CD27, integrin alpha-M, ly6c, ly6g, NCAM-1, and ter119). These cells also express the transcription factors GATA-1, GATA-2, and MITF, but not C/EBPa.

capable of

http://purl.obolibrary.org/obo/GO_0060374

definition

A progenitor cell of the mast cell lineage. Markers for this cell are FceRIa-low, CD117-positive, CD9-positive, T1/ST2-positive, SCA1-negative, and lineage-negative.

develops_from

http://purl.obolibrary.org/obo/CL_0002028

has high plasma membrane amount

http://purl.obolibrary.org/obo/PR_000009143

has low plasma membrane amount

http://purl.obolibrary.org/obo/PR_000002065

http://purl.obolibrary.org/obo/PR_000007431

has part

http://purl.obolibrary.org/obo/PR_000007857

http://purl.obolibrary.org/obo/PR_000007858

has plasma membrane part

http://purl.obolibrary.org/obo/PR_000016401

http://purl.obolibrary.org/obo/PR_000005178

has_exact_synonym

MCP

has_related_synonym

colony forming unit mast cell

CFU-MC

CFU-Mast

label

mast cell progenitor

lacks_part

http://purl.obolibrary.org/obo/PR_000005307

lacks_plasma_membrane_part

http://purl.obolibrary.org/obo/PR_000001889

http://purl.obolibrary.org/obo/PR_000002981

http://purl.obolibrary.org/obo/PR_000001084

http://purl.obolibrary.org/obo/PR_000001963

http://purl.obolibrary.org/obo/PR_000001012

http://purl.obolibrary.org/obo/PR_000001004

http://purl.obolibrary.org/obo/PR_000001289

http://purl.obolibrary.org/obo/PR_000001083

http://purl.obolibrary.org/obo/PR_000002978

http://purl.obolibrary.org/obo/PR_000001002

http://purl.obolibrary.org/obo/PR_000001020

http://purl.obolibrary.org/obo/PR_000002979

http://purl.obolibrary.org/obo/PR_000001024

http://purl.obolibrary.org/obo/PR_000001839

http://purl.obolibrary.org/obo/PR_000002980

prefixIRI

CL:0000831

prefLabel

mast cell progenitor

treeView

http://purl.obolibrary.org/obo/CL_0002028

subClassOf

http://purl.obolibrary.org/obo/CL_0000763

http://purl.obolibrary.org/obo/PR_000050567

http://purl.obolibrary.org/obo/CL_0000839

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http://purl.obolibrary.org/obo/CL_0000831 Experimental Factor Ontology / 实验性因素本体 LOOM
http://purl.obolibrary.org/obo/CL_0000831 Experimental Factor Ontology / 实验性因素本体 SAME_URI