Preferred Name

Phosphatidylinositide 3-Kinase Inhibitor

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2152

CHEBI_ID

CHEBI:50914

code

C2152

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978

Contributing_Source

CTRP

DEFINITION

Any substance that inhibits phosphatidylinositol 3-kinase (phosphatidylinositide 3-kinase), an enzyme that catalyzes the phosphorylation of the 3 position hydroxyl group of the inositol ring of phosphatidylinositol and functions as an intracellular signal transducer in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. Inhibition of phosphatidylinositol 3-kinase produces antiproliferative and antiangiogenic effects.

Display_Name

PI3K Inhibitor

FULL_SYN

Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Inhibitor

Phosphatidylinositol 3-kinase Inhibitor

PI3-Kinase Inhibitors

PI3K Inhibitor

Phosphatidylinositide 3-Kinase Inhibitor

Has_Target

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17270

label

Phosphatidylinositide 3-Kinase Inhibitor

Legacy Concept Name

Phosphatidylinositide_3-Kinase_Inhibitor

Preferred_Name

Phosphatidylinositide 3-Kinase Inhibitor

prefixIRI

Thesaurus:C2152

prefLabel

Phosphatidylinositide 3-Kinase Inhibitor

Semantic_Type

Chemical Viewed Functionally

UMLS_CUI

C1519050

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1404

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1742

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C163758

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