Human Phenotype Ontology / 人类表型本体

Last uploaded: September 7, 2023
Preferred Name

Acute coronary syndrome

Definitions

The term acute coronary syndrome (ACS) refers to any group of clinical symptoms compatible with acute myocardial ischemia and includes unstable angina (UA), non-ST-segment elevation myocardial infarction (NSTEMI), and ST-segment elevation myocardial infarction (STEMI). A diagnosis of NSTEMI can be made when the ischemia is sufficiently severe to cause myocardial damage that results in the release of a biomarker of myocardial necrosis into the circulation (cardiac-specific troponins T or I, or muscle and brain fraction of creatine kinase [CK-MB]). In contrast, the patient is considered to have experienced UA if no such biomarker can be detected in the bloodstream hours after the initial onset of ischemic chest pain. Unstable angina exhibits 1 or more of 3 principal presentations: (1) rest angina (usually lasting >20 minutes), (2) new-onset (<2 months previously) severe angina, and (3) a crescendo pattern of occurrence (increasing in intensity, duration, frequency, or any combination of these factors).

ID

http://purl.obolibrary.org/obo/HP_0033678

comment

A diagnosis of NSTEMI can be made when the ischemia is sufficiently severe to cause myocardial damage that results in the release of a biomarker of myocardial necrosis into the circulation (cardiac-specific troponins T or I, or muscle and brain fraction of creatine kinase [CK-MB]). In contrast, the patient is considered to have experienced UA if no such biomarker can be detected in the bloodstream hours after the initial onset of ischemic chest pain. Unstable angina exhibits 1 or more of 3 principal presentations: (1) rest angina (usually lasting >20 minutes), (2) new-onset (<2 months previously) severe angina, and (3) a crescendo pattern of occurrence (increasing in intensity, duration, frequency, or any combination of these factors).

creator

https://orcid.org/0000-0002-0736-9199

date

2021-03-03T20:22:24Z

definition

The term acute coronary syndrome (ACS) refers to any group of clinical symptoms compatible with acute myocardial ischemia and includes unstable angina (UA), non-ST-segment elevation myocardial infarction (NSTEMI), and ST-segment elevation myocardial infarction (STEMI).

has_obo_namespace

human_phenotype

id

HP:0033678

label

Acute coronary syndrome

notation

HP:0033678

prefLabel

Acute coronary syndrome

treeView

http://purl.obolibrary.org/obo/HP_0011025

subClassOf

http://purl.obolibrary.org/obo/HP_0011025

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/MONDO_0005542 Mondo Disease Ontology / Mondo疾病本体 LOOM
http://www.ebi.ac.uk/efo/EFO_0005672 Experimental Factor Ontology / 实验性因素本体 LOOM
http://purl.bioontology.org/ontology/MESH/D054058 Medical Subject Headings / 医学主题词表 LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C53652 National Cancer Institute Thesaurus / 美国国家癌症研究所词典 LOOM