| Preferred Name |
Proheparin-Binding EGF-Like Growth Factor |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118380 |
| code |
C118380 |
| DEFINITION |
Proheparin-binding EGF-like growth factor (208 aa, ~23 kDa) is encoded by the human HBEGF gene. This protein plays a role in both heart valve formation and mitogenesis for fibroblasts and smooth muscle cells. |
| DesignNote |
The active form of the growth factor, called heparin-binding EGF-like growth factor, is produced by two proteolytic cleavage events that remove 62 N-terminal amino acids and 60 amino acids from the C-terminus of proheparin-binding EGF-like growth factor. The precursor is a type I membrane protein and the mature form is a secreted protein. (UniProt) |
| FULL_SYN |
Proheparin-Binding EGF-Like Growth Factor Pro-HB-EGF |
| label |
Proheparin-Binding EGF-Like Growth Factor |
| OMIM_Number |
126150 |
| Preferred_Name |
Proheparin-Binding EGF-Like Growth Factor |
| prefixIRI |
Thesaurus:C118380 |
| prefLabel |
Proheparin-Binding EGF-Like Growth Factor |
| Semantic_Type |
Amino Acid, Peptide, or Protein |
| Swiss_Prot |
Q99075 |
| UMLS_CUI |
C3888283 |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.obolibrary.org/obo/PR_000008459 | Protein Ontology / 蛋白质本体 | LOOM |