loading...| Preferred Name |
Adenovirus Encoding Human Aquaporin-1 |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C68932 |
| code |
C68932 |
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 |
| Contributing_Source |
CTRP |
| DEFINITION |
A replication-deficient, recombinant adenovirus encoding human aquaporin-1 with potential membrane water channel activity. Upon transfection of salivary glands, adenovirus encoding human aquaporin-1 (AdhAQP1) directs human aquaporin-1 (hAQP1) expression in the apical and basolateral plasma membranes of salivary secretory cells, which may result in increased saliva production. hAQP1, a water channel protein, is one of several highly conserved water channel proteins that mediate water permeability in cells of water-transporting tissues. |
| Display_Name |
Adenovirus Encoding Human Aquaporin-1 |
| FULL_SYN |
AdhAQP1 Adenovirus Encoding Human Aquaporin-1 AAV2hAQP1 AAV2-hAQP1 AAV2 hAQP1 |
| label |
Adenovirus Encoding Human Aquaporin-1 |
| Legacy Concept Name |
Adenovirus_Encoding_Human_Aquaporin-1 |
| NCI_Drug_Dictionary_ID |
547184 |
| NCI_META_CUI |
CL374275 |
| PDQ_Closed_Trial_Search_ID |
547184 |
| PDQ_Open_Trial_Search_ID |
547184 |
| Preferred_Name |
Adenovirus Encoding Human Aquaporin-1 |
| prefixIRI |
Thesaurus:C68932 |
| prefLabel |
Adenovirus Encoding Human Aquaporin-1 |
| Semantic_Type |
Pharmacologic Substance |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| There are currently no mappings for this class. | |||