loading...| Preferred Name |
Nucleic Acid Denaturation |
| Synonyms |
Acid Denaturation, Nucleic |
| Definitions |
Disruption of the secondary structure of nucleic acids by heat, extreme pH or chemical treatment. Double strand DNA is "melted" by dissociation of the non-covalent hydrogen bonds and hydrophobic interactions. Denatured DNA appears to be a single-stranded flexible structure. The effects of denaturation on RNA are similar though less pronounced and largely reversible. |
| ID |
http://purl.bioontology.org/ontology/MESH/D009691 |
| altLabel |
Acid Denaturation, Nucleic Denaturation, DNA RNA Denaturation DNA Denaturation Denaturation, Nucleic Acid Denaturation, RNA Nucleic Acid Denaturations DNA Melting |
| AN |
IM general only; coord NIM with DNA or RNA or specific (IM) |
| AQL |
DE GE PD RE |
| cui |
C0028600 C1720789 C1720790 |
| DC |
1 |
| definition |
Disruption of the secondary structure of nucleic acids by heat, extreme pH or chemical treatment. Double strand DNA is "melted" by dissociation of the non-covalent hydrogen bonds and hydrophobic interactions. Denatured DNA appears to be a single-stranded flexible structure. The effects of denaturation on RNA are similar though less pronounced and largely reversible. |
| DX |
19700101 |
| FX |
D020871 |
| HN |
70(67) |
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000528 |
| Inverse of RO | |
| Machine permutation |
70 |
| MDA |
19990101 |
| MMR |
20160617 |
| MN |
G05.627 E05.393.640 G02.111.603 |
| notation |
D009691 |
| prefLabel |
Nucleic Acid Denaturation |
| TERMUI |
T674637 T674636 T674638 T028819 |
| TH |
NLM (2006) NLM (1967) |
| tui |
T070 |
| subClassOf |
http://purl.bioontology.org/ontology/MESH/D055614 |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| There are currently no mappings for this class. | |||