loading...| Preferred Name |
Codon, Nonsense |
| Synonyms |
Nonsense Mutation, Ochre |
| Definitions |
An amino acid-specifying codon that has been converted to a stop codon (CODON, TERMINATOR) by mutation. Its occurance is abnormal causing premature termination of protein translation and results in production of truncated and non-functional proteins. A nonsense mutation is one that converts an amino acid-specific codon to a stop codon. |
| ID |
http://purl.bioontology.org/ontology/MESH/D018389 |
| altLabel |
Nonsense Mutation, Ochre Mutation, Opal Nonsense Codons, Premature Termination Mutation, Amber Nonsense Mutations, Opal Nonsense Nonsense Codons, Ochre Nonsense Codon, Ochre Ochre Nonsense Mutation Amber Nonsense Mutations Premature Stop Codons Codons, Amber Nonsense Premature Termination Codons Mutations, Ochre Nonsense Nonsense Codon, Opal Unassigned Codon Nonsense Codons, Amber Nonsense Mutations, Ochre Nonsense Codons, Opal Ochre Nonsense Mutations Ochre Nonsense Codons Premature Termination Codon Stop Codon, Premature Nonsense Codon Codons, Nonsense Opal Nonsense Mutation Opal Nonsense Mutations Amber Nonsense Codon Amber Nonsense Mutation Nonsense Mutations Mutation, Nonsense Termination Codons, Premature Ochre Nonsense Codon Amber Nonsense Codons Nonsense Mutation Codons, Premature Stop Termination Codon, Premature Nonsense Mutation, Amber Codon, Unassigned Codons, Ochre Nonsense Unassigned Codons Codon, Premature Termination Mutation, Ochre Nonsense Mutations, Nonsense Codon, Ochre Nonsense Stop Codons, Premature Mutations, Amber Nonsense Premature Stop Codon Nonsense Codons Codon, Premature Stop Codons, Opal Nonsense Opal Nonsense Codon Nonsense Mutations, Opal Nonsense Mutation, Opal Codon, Amber Nonsense Opal Nonsense Codons Nonsense Codon, Amber Nonsense Mutations, Amber Codon, Opal Nonsense Codons, Unassigned Codon, Termination, Premature |
| AN |
for amber or ochre suppressor mutations use SUPPRESSION, GENETIC |
| AQL |
AD AE AG AI AN BI BL CF CH CL CS DE EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR |
| cui |
C0242612 C0544885 C1956151 C1956154 C1956156 C0917893 C1956155 C1956152 C1956153 |
| DC |
1 |
| definition |
An amino acid-specifying codon that has been converted to a stop codon (CODON, TERMINATOR) by mutation. Its occurance is abnormal causing premature termination of protein translation and results in production of truncated and non-functional proteins. A nonsense mutation is one that converts an amino acid-specific codon to a stop codon. A codon that is not assigned to an amino acid and is not a stop codon (CODON, TERMINATOR). Although they may lead to premature termination of translation, unassigned codons do not bind translation release factors (PEPTIDE TERMINATION FACTORS), as do stop codons. A mutation that converts a sense codon (CODON) into a stop codon (CODON, TERMINATOR) or an unassigned codon and leads to the formation of truncated proteins. |
| DX |
19950101 |
| HN |
95 |
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000528 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000378 |
| Inverse of RB |
0 |
| Machine permutation |
95 |
| MDA |
19940603 |
| MMR |
20130709 |
| MN |
G05.365.590.195 D13.444.735.544.355.250.235 G05.360.335.355.250.235 |
| notation |
D018389 |
| prefLabel |
Codon, Nonsense |
| TERMUI |
T412074 T054832 T686247 T054831 T686201 T414291 T686203 T412075 T686248 T054830 T414292 T414290 T412076 T686204 T686202 T686200 |
| TH |
NLM (2008) NLM (2001) NLM (1995) |
| tui |
T049 T045 T086 |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.bioontology.org/ontology/LNC/LA6699-8 | Logical Observation Identifier Names and Codes / 逻辑观察标识符名称和代码 | CUI |