loading...| Preferred Name |
Apoptosis |
| Synonyms |
Apoptosis, Intrinsic Pathway |
| Definitions |
A regulated cell death mechanism characterized by distinctive morphologic changes in the nucleus and cytoplasm, including the endonucleolytic cleavage of genomic DNA, at regularly spaced, internucleosomal sites, i.e., DNA FRAGMENTATION. It is genetically programmed and serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth. |
| ID |
http://purl.bioontology.org/ontology/MESH/D017209 |
| altLabel |
Apoptosis, Intrinsic Pathway Caspase Dependent Apoptosis Programmed Cell Death, Type I Apoptoses, Extrinsic Pathway Classical Apoptosis Extrinsic Pathway Apoptoses Programmed Cell Death Apoptoses, Intrinsic Pathway Intrinsic Pathway Apoptoses Cell Death, Programmed Apoptosis, Classical Apoptosis, Caspase-Dependent Apoptosis, Extrinsic Pathway Apoptosis, Classic Extrinsic Pathway Apoptosis Intrinsic Pathway Apoptosis Classic Apoptosis Classic Apoptoses Caspase-Dependent Apoptosis |
| AN |
general or unspecified, note specifics |
| AQL |
DE GE IM PH RE |
| cui |
C1720827 C0162638 C1720828 C1707312 |
| DC |
1 |
| definition |
A regulated cell death mechanism characterized by distinctive morphologic changes in the nucleus and cytoplasm, including the endonucleolytic cleavage of genomic DNA, at regularly spaced, internucleosomal sites, i.e., DNA FRAGMENTATION. It is genetically programmed and serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth. Apoptosis that is triggered via cell stress and mitochondrial damage. Physiological forms of regulated cell death that occur during growth and development and tissue turnover. Apoptosis that is triggered via CELL SURFACE RECEPTORS such as TUMOR NECROSIS FACTOR RECEPTORS and DEATH DOMAIN RECEPTORS. |
| DX |
19930101 |
| FX |
D053418 D041722 D020169 D053468 D029563 D009336 D020287 |
| HN |
93 |
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000528 http://purl.bioontology.org/ontology/MESH/Q000235 |
| Inverse of RO |
http://purl.bioontology.org/ontology/MESH/D020169 http://purl.bioontology.org/ontology/MESH/D053418 http://purl.bioontology.org/ontology/MESH/D017637 http://purl.bioontology.org/ontology/MESH/D016923 http://purl.bioontology.org/ontology/MESH/D009336 http://purl.bioontology.org/ontology/MESH/D041722 http://purl.bioontology.org/ontology/MESH/D020170 http://purl.bioontology.org/ontology/MESH/D029563 http://purl.bioontology.org/ontology/MESH/D020287 |
| Machine permutation |
93 |
| MDA |
19920507 |
| MMR |
20210630 |
| MN |
G04.146.954.035 |
| notation |
D017209 |
| prefLabel |
Apoptosis |
| TERMUI |
T051308 T663494 T000946888 T615426 T000946886 T000946887 T000945904 T663495 |
| TH |
NLM (2006) NLM (1993) NLM (2007) NLM (2020) |
| tui |
T116 T043 T123 |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17557 | National Cancer Institute Thesaurus / 美国国家癌症研究所词典 | LOOM |