| Preferred Name |
CD3 Complex |
| Synonyms |
Antigens, CD3 |
| Definitions |
Complex of at least five membrane-bound polypeptides in mature T-lymphocytes that are non-covalently associated with one another and with the T-cell receptor (RECEPTORS, ANTIGEN, T-CELL). The CD3 complex includes the gamma, delta, epsilon, zeta, and eta chains (subunits). When antigen binds to the T-cell receptor, the CD3 complex transduces the activating signals to the cytoplasm of the T-cell. The CD3 gamma and delta chains (subunits) are separate from and not related to the gamma/delta chains of the T-cell receptor (RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA). |
| ID |
http://purl.bioontology.org/ontology/MESH/D017252 |
| altLabel |
Antigens, CD3 T3 Complex CD3 Antigens Antigens, T3 T3 Antigen CD3 Antigen Antigen, CD3 Antigen, T3 T3 Antigens |
| AQL |
AD AE AG AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR |
| cui |
C0108779 |
| DC |
1 |
| definition |
Complex of at least five membrane-bound polypeptides in mature T-lymphocytes that are non-covalently associated with one another and with the T-cell receptor (RECEPTORS, ANTIGEN, T-CELL). The CD3 complex includes the gamma, delta, epsilon, zeta, and eta chains (subunits). When antigen binds to the T-cell receptor, the CD3 complex transduces the activating signals to the cytoplasm of the T-cell. The CD3 gamma and delta chains (subunits) are separate from and not related to the gamma/delta chains of the T-cell receptor (RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA). |
| DX |
19930101 |
| FX |
D011948 |
| HN |
2018 (1993); use T3 ANTIGEN COMPLEX 1983-92; use ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE 1988-92 |
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000528 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000172 |
| Inverse of RB |
0 |
| Inverse of RO | |
| Machine permutation |
2018; see ANTIGENS, CD3 1993-2017; CD3 COMPLEX was indexed under RECEPTORS, ANTIGEN, T-CELL 1990-92; under ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE 1988-92; under ANTIGENS, SURFACE 1983-87; and under ANTIGENS 1983-84; for T3 ANTIGENS see ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE 1988-92 |
| Mapped from |
http://purl.bioontology.org/ontology/MESH/C485468 http://purl.bioontology.org/ontology/MESH/C472562 http://purl.bioontology.org/ontology/MESH/C452842 http://purl.bioontology.org/ontology/MESH/C121704 |
| MDA |
19920507 |
| MMR |
20170602 |
| MN |
D23.050.301.264.894.095 D23.101.100.894.095 |
| notation |
D017252 |
| prefLabel |
CD3 Complex |
| TERMUI |
T051425 T051424 T051429 T051427 T051428 T051426 T051430 |
| TH |
NLM (1993) |
| tui |
T116 T129 |
| subClassOf |