loading...| Preferred Name |
Interleukin-12 |
| Synonyms |
Interleukin 12 p70 |
| Definitions |
A heterodimeric cytokine that plays a role in innate and adaptive immune responses. Interleukin-12 is a 70 kDa protein that is composed of covalently linked 40 kDa and 35 kDa subunits. It is produced by DENDRITIC CELLS; MACROPHAGES and a variety of other immune cells and plays a role in the stimulation of INTERFERON-GAMMA production by T-LYMPHOCYTES and NATURAL KILLER CELLS. |
| ID |
http://purl.bioontology.org/ontology/MESH/D018664 |
| altLabel |
Interleukin 12 p70 Edodekin Alfa Interleukin-12 p70 Natural Killer Cell Stimulatory Factor IL-12 IL 12 Interleukin 12 IL-12 p70 Cytotoxic Lymphocyte Maturation Factor IL12 |
| AQL |
AD AE AG AI AN BI BL CF CH CL CS DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UR |
| cui |
C3665495 C0123759 |
| DC |
1 |
| definition |
A heterodimeric cytokine that plays a role in innate and adaptive immune responses. Interleukin-12 is a 70 kDa protein that is composed of covalently linked 40 kDa and 35 kDa subunits. It is produced by DENDRITIC CELLS; MACROPHAGES and a variety of other immune cells and plays a role in the stimulation of INTERFERON-GAMMA production by T-LYMPHOCYTES and NATURAL KILLER CELLS. |
| DX |
19950101 |
| FX |
D000069549 D007111 |
| HN |
1995 (1991) |
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000528 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000172 |
| Inverse of RB |
187348-17-0 0 |
| Inverse of RO | |
| isa | |
| Machine permutation |
1995; INTERLEUKIN 12 was indexed under INTERLEUKINS 1991-1994; INTERLEUKIN-12 P70 was indexed under INTERLEUKIN-12 2003-2006 |
| Mapped from |
http://purl.bioontology.org/ontology/MESH/C513398 http://purl.bioontology.org/ontology/MESH/C107398 http://purl.bioontology.org/ontology/MESH/C513581 |
| MDA |
19940419 |
| MMR |
20181010 |
| MN |
D23.529.374.465.512 D12.776.467.374.465.512 D12.644.276.374.465.512 |
| notation |
D018664 |
| PA |
D000276 D020533 |
| prefLabel |
Interleukin-12 |
| TERMUI |
T055565 T429787 T669102 T055563 T055561 T055562 T373474 T550497 T669076 T055566 |
| TH |
USAN (1998) NLM (2000) NLM (2007) NLM (1995) |
| tui |
T116 T129 T121 |
| subClassOf |