Preferred Name

NADH Dehydrogenase (Ubiquinone)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118184

code

C118184

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142800

Contributing_Source

CTRP

DEFINITION

A complex of over 40 proteins found in the inner mitochondrial membrane. This protein complex catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q10) and plays a role in the initiation of the mitochondrial electron transport chain.

DesignNote

There are 14 core subunits found in all organisms and over 30 accessory subunits, which may play a role in the assembly or stability of the complex. Of the 14 core subunits, 7 are encoded by nuclear genes and 7 are encoded by mitochondrial genes.

Display_Name

NADH Dehydrogenase (Ubiquinone)

FULL_SYN

Ubiquinone Reductase

NADH-Ubiquinone Oxidoreductase

NADH:Ubiquinone Oxidoreductase

Reduced Nicotinamide Adenine Dinucleotide-Coenzyme Q Reductase

NADH:Ubiquinone Oxidoreductase Complex

Complex I (Electron Transport Chain)

Complex I (NADH:Q1 Oxidoreductase)

NADH:Ubiquinone Reductase (H(+)-Translocating)

Respiratory Complex I

NADH2 Dehydrogenase (Ubiquinone)

Mitochondrial Respiratory Chain Complex I

Dihydronicotinamide Adenine Dinucleotide-Coenzyme Q Reductase

Electron Transfer Complex I

EC 1.6.5.3

Complex I

NADH-Ubiquinone Reductase

NADH-CoQ Oxidoreductase

NADH Dehydrogenase (Ubiquinone)

NADH-Coenzyme Q Oxidoreductase

NADH-Q6 Oxidoreductase

Mitochondrial Electron Transport Complex I

DPNH-Coenzyme Q Reductase

Type 1 Dehydrogenase

NADH-Coenzyme Q Reductase

DPNH-Ubiquinone Reductase

Mitochondrial Electron Transport Complex 1

NADH-CoQ Reductase

Coenzyme Q Reductase

Complex 1 Dehydrogenase

NADH Coenzyme Q1 Reductase

Complex I (Mitochondrial Electron Transport)

Mitochondrial Complex I

NADH-Ubiquinone-1 Reductase

label

NADH Dehydrogenase (Ubiquinone)

Preferred_Name

NADH Dehydrogenase (Ubiquinone)

prefixIRI

Thesaurus:C118184

prefLabel

NADH Dehydrogenase (Ubiquinone)

Semantic_Type

Enzyme

Amino Acid, Peptide, or Protein

UMLS_CUI

C0171406

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C21176

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