loading...| Preferred Name |
Polihexanide Solution |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121637 |
| code |
C121637 |
| Concept_In_Subset | |
| DEFINITION |
A solution containing the polymer polihexanide, with potential antimicrobial, disinfectant and wound healing activities. Upon application to a wound, polihexanide strongly binds to the wound surface and exerts an antiseptic effect through the binding of the positively charged guanidine groups of polihexanide with the negatively charged phospholipids of the bacterial cell membrane. This compromises the stability of the bacterial cell membrane, which results in the leakage of cytoplasmic components and leads to bacterial cell death. In addition, polihexanide accelerates wound healing by promoting epithelial cell migration and proliferation. |
| FULL_SYN |
PHMB Solution Polyhexanide Solution Polihexanide Solution Polyhexamethylenebiguanide Solution |
| label |
Polihexanide Solution |
| NCI_Drug_Dictionary_ID |
770448 |
| PDQ_Closed_Trial_Search_ID |
770448 |
| PDQ_Open_Trial_Search_ID |
770448 |
| Preferred_Name |
Polihexanide Solution |
| prefixIRI |
Thesaurus:C121637 |
| prefLabel |
Polihexanide Solution |
| Semantic_Type |
Pharmacologic Substance |
| UMLS_CUI |
C4053774 |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| There are currently no mappings for this class. | |||