Preferred Name

Platelet-Derived Growth Factor-AA

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128285

code

C128285

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142800

Contributing_Source

CTRP

DEFINITION

A disulfide-linked homodimeric protein complex comprised of 2 platelet-derived growth factor subunit A proteins. This dimeric growth factor binds to a homodimeric receptor comprised of two platelet-derived growth factor receptor alpha proteins. Ligand binding activates the intrinsic tyrosine-protein kinase activity of the receptor complex and initiates signal transduction pathways.

Display_Name

Platelet-Derived Growth Factor-AA

FULL_SYN

Platelet-Derived Growth Factor-AA

PDGF-AA

label

Platelet-Derived Growth Factor-AA

Preferred_Name

Platelet-Derived Growth Factor-AA

prefixIRI

Thesaurus:C128285

prefLabel

Platelet-Derived Growth Factor-AA

Related_To_Genetic_Biomarker

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C24665

Semantic_Type

Amino Acid, Peptide, or Protein

UMLS_CUI

C0210108

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C21176

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