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loading...| Preferred Name |
Pyruvate Kinase PKM Isoform M2 Dimer |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C136626 |
| code |
C136626 |
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 |
| Contributing_Source |
CTRP |
| DEFINITION |
A homodimer of the pyruvate kinase PKM isoform M2. This enzyme complex promotes cellular metabolism and is overexpressed in tumors. |
| DesignNote |
M2-PK may be used as a biomarker for colorectal cancer in fecal testing or as a marker for pancreatic, gastric, esophageal, colorectal and cholangiocellular cancer in plasma screening. |
| Display_Name |
Pyruvate Kinase PKM Isoform M2 Dimer |
| FULL_SYN |
Pyruvate Kinase PKM Isoform M2 Dimer Tumor M2-PK M2-PK |
| label |
Pyruvate Kinase PKM Isoform M2 Dimer |
| NCI_META_CUI |
CL524466 |
| Preferred_Name |
Pyruvate Kinase PKM Isoform M2 Dimer |
| prefixIRI |
Thesaurus:C136626 |
| prefLabel |
Pyruvate Kinase PKM Isoform M2 Dimer |
| Semantic_Type |
Enzyme Amino Acid, Peptide, or Protein |
| subClassOf |
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