loading...| Preferred Name |
Kallikrein Inhibitor MDPK67b |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180588 |
| code |
C180588 |
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 |
| Contributing_Source |
GDC |
| DEFINITION |
A recombinant protein-based inhibitor of numerous types of kallikrein-related peptidases (KLKs), with potential antineoplastic activity. Upon administration, KLK inhibitor MDPK67b targets and inhibits various KLKs, including KLK2, KLK4, KLK5 and KLK14. This inhibits KLK-mediated signaling and inhibits the proliferation of tumor cells in which these KLKs are overexpressed. Deregulation of KLKs is associated with some types of cancers. |
| FULL_SYN |
Kallikrein Inhibitor MDPK67b KLK Inhibitor MDPK67b MDPK67b MDPK 67b MDPK-67b |
| Has_Target | |
| label |
Kallikrein Inhibitor MDPK67b |
| NCI_Drug_Dictionary_ID |
805502 |
| NCI_META_CUI |
CL1662948 |
| Preferred_Name |
Kallikrein Inhibitor MDPK67b |
| prefixIRI |
Thesaurus:C180588 |
| prefLabel |
Kallikrein Inhibitor MDPK67b |
| Semantic_Type |
Pharmacologic Substance |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| There are currently no mappings for this class. | |||