loading...| Preferred Name |
Anti-Wolbachia Agent AWZ1066S |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C185291 |
| code |
C185291 |
| Concept_In_Subset | |
| DEFINITION |
An orally bioavailable synthetic compond that is active against the bacterium Wolbachia and that can potentially be used to treat diseases caused by namatodes of the family Filariodidea, such as lymphatic filariasis and onchocerciasis. Upon oral administration, the anti-Wolbachia agent AWZ1066S specifically kills Wolbachia through an as of yet not fully identified mechanism of action (MoA). In filarial nematodes-infected humans, adult worms need Wolbachia in order to grow, reproduce, and survive. Targeting Wolbachia may indirectly kill the adult parasitic worms and prevent filariasis. |
| FULL_SYN |
AWZ 1066S AWZ-1066S AWZ1066S Anti-Wolbachia Agent AWZ1066S |
| label |
Anti-Wolbachia Agent AWZ1066S |
| NCI_Drug_Dictionary_ID |
808171 |
| NCI_META_CUI |
CL1773385 |
| Preferred_Name |
Anti-Wolbachia Agent AWZ1066S |
| prefixIRI |
Thesaurus:C185291 |
| prefLabel |
Anti-Wolbachia Agent AWZ1066S |
| Semantic_Type |
Pharmacologic Substance |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| There are currently no mappings for this class. | |||