National Cancer Institute Thesaurus / 美国国家癌症研究所词典

Last uploaded: September 7, 2023

Preferred Name	VEGF:VEGFR Complex
ID	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122771
code	C122771
Concept_In_Subset	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142800
Contributing_Source	CTRP
DEFINITION	A ligand-receptor complex comprised of a homodimer of vascular endothelial growth factor (VEGF) family proteins bound to a heterodimer of vascular endothelial growth factor receptor (VEGFR) family proteins. Ligand binding triggers receptor dimerization and cross-receptor tyrosine phosphorylation, which promotes downstream signal transduction.
Display_Name	VEGF:VEGFR Complex
FULL_SYN	Vascular Endothelial Growth Factor-Vascular Endothelial Growth Factor Receptor Complex VEGF-VEGFR Complex VEGF/VEGFR Complex VEGF:VEGFR Complex Vascular Endothelial Growth Factor:Vascular Endothelial Growth Factor Receptor Complex Vascular Endothelial Growth Factor/Vascular Endothelial Growth Factor Receptor Complex
label	VEGF:VEGFR Complex
Preferred_Name	VEGF:VEGFR Complex
prefixIRI	Thesaurus:C122771
prefLabel	VEGF:VEGFR Complex
Semantic_Type	Amino Acid, Peptide, or Protein
UMLS_CUI	C4053885
subClassOf	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C21176

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