loading...| Preferred Name |
SIRPA V2 Allele |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C189879 |
| code |
C189879 |
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 |
| Contributing_Source |
CTRP |
| DEFINITION |
Human SIRPA V2 allele is located within 20p13 and is approximately 45 kb in length. This allele, which encodes an isoform of tyrosine-protein phosphatase non-receptor type substrate 1 protein with 12 amino acid substitutions and 1 amino acid deletion in the immunoglobulin-like V-type domain, is involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. |
| DesignNote |
The protein encoded by SIRPA V2 (CAA71403.1) has the following amino acid variations: D131del, L44S, T50S, T52I, R54H, A57V, G75A, D95E, L96S, N100E, R107S, G109S and V132T. |
| Display_Name |
SIRPA V2 Allele |
| EntrezGene_ID |
140885 |
| FULL_SYN |
SIRPalpha V2 Allele SIRPA Variant 2 Allele Signal Regulatory Protein Alpha V2 Allele SIRPA V2 Allele Signal Regulatory Protein-Alpha V2 Allele SIRPalpha Variant 2 Allele |
| GenBank_Accession_Number |
Y10375 |
| label |
SIRPA V2 Allele |
| NCI_META_CUI |
CL1798583 |
| OMIM_Number |
602461 |
| Preferred_Name |
SIRPA V2 Allele |
| prefixIRI |
Thesaurus:C189879 |
| prefLabel |
SIRPA V2 Allele |
| Semantic_Type |
Gene or Genome |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| There are currently no mappings for this class. | |||