loading...| Preferred Name |
Telomere Maintenance Gene |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20338 |
| code |
C20338 |
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 |
| Contributing_Source |
CTRP |
| DEFINITION |
Telomere Maintenance Genes encode specialized proteins bound to telomeric DNA repeats and directly involved in maintaining/protecting chromosome telomere ends to prevent a damage response that halts cell proliferation. Telomerase, which lengthens telomeric DNA by RNA-templated addition of repeated DNA sequences, is regulated by proteins that bind to the telomeric DNA repeats and to additional proteins to assemble a higher-order telomeric complex. (NCI) |
| Display_Name |
Telomere Maintenance Gene |
| FULL_SYN |
Telomere Maintenance Gene |
| label |
Telomere Maintenance Gene |
| Legacy Concept Name |
Telomere_Maintenance_Gene |
| Preferred_Name |
Telomere Maintenance Gene |
| prefixIRI |
Thesaurus:C20338 |
| prefLabel |
Telomere Maintenance Gene |
| Semantic_Type |
Gene or Genome |
| UMLS_CUI |
C1336700 |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| There are currently no mappings for this class. | |||