Preferred Name

Ornithine Decarboxylase Inhibitor

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2088

code

C2088

DEFINITION

Any substance that inhibits ornithine decarboxylase, an enzyme that catalyzes the decarboxylation of ornithine, the rate-limiting, commiting reaction in polyamine synthesis. Polyamines are important for stabilizing DNA structure, for the DNA double strand-break repair pathway, and as antioxidants, and inhibition of ornithine decarboxylase inhibits cell growth.

FULL_SYN

Ornithine Decarboxylase Inhibitor

Ornithine Decarboxylase Inhibitors

label

Ornithine Decarboxylase Inhibitor

Legacy Concept Name

Ornithine_Decarboxylase_Inhibitor

Preferred_Name

Ornithine Decarboxylase Inhibitor

prefixIRI

Thesaurus:C2088

prefLabel

Ornithine Decarboxylase Inhibitor

Semantic_Type

Chemical Viewed Functionally

UMLS_CUI

C1518618

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C471

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2076

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