Preferred Name

Chaperone Protein Gene

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25802

code

C25802

DEFINITION

Genes that encode cytoplasmic proteins of both prokaryotes and eukaryotes that bind to nascent or unfolded polypeptides and ensure correct folding or transport. Chaperone proteins do not covalently bind to their targets and do not form part of the finished product. Heat-shock proteins are an important sub set of chaperones. Three major families are recognised, the chaperonins (groEL and hsp60), the hsp70 family and the hsp90 family. Outside these major families are other proteins with similar functions including nucleoplasmin, secB and T-cell receptor associated protein.

FULL_SYN

Chaperone Gene

Chaperone Protein Gene

Gene_Encodes_Product

Chaperone

label

Chaperone Protein Gene

Legacy Concept Name

Chaperone_Gene

Preferred_Name

Chaperone Protein Gene

prefixIRI

Thesaurus:C25802

prefLabel

Chaperone Protein Gene

Semantic_Type

Gene or Genome

UMLS_CUI

C1332924

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16612

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