loading...| Preferred Name |
Bacitracin Zinc |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28857 |
| CAS_Registry |
1405-89-6 |
| code |
C28857 |
| Concept_In_Subset | |
| Contributing_Source |
FDA |
| DEFINITION |
The zinc salt form of bacitracin, a complex of cyclic polypeptide antibiotics, mainly bacitracin A, produced by spore-forming organisms belonging to the licheniformin group of the Bacillus subtilis with antibacterial activity. Bacitracin zinc binds to C55-isoprenyl pyrophosphate, a biphosphate lipid transport molecule that carries the building blocks of the peptidoglycan bacterial cell wall, thereby interfering with the enzymatic dephosphorylation of the C55-isoprenyl pyrophosphate and preventing peptidoglycan synthesis which leads to cell lysis. |
| FDA_UNII_Code |
89Y4M234ES |
| FULL_SYN |
Ziba-Rx BACITRACIN ZINC Bacitracin Zinc |
| Has_Free_Acid_Or_Base_Form | |
| label |
Bacitracin Zinc |
| Legacy Concept Name |
Bacitracin_Zinc |
| Preferred_Name |
Bacitracin Zinc |
| prefixIRI |
Thesaurus:C28857 |
| prefLabel |
Bacitracin Zinc |
| Semantic_Type |
Pharmacologic Substance Antibiotic |
| UMLS_CUI |
C0043483 |
| subClassOf |